DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3862 and Rcbtb2

DIOPT Version :9

Sequence 1:	NP_608550.1	Gene:	CG3862 / 33261	FlyBaseID:	FBgn0031286	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	XP_038949091.1	Gene:	Rcbtb2 / 290363	RGDID:	735048	Length:	585	Species:	Rattus norvegicus

Alignment Length:	335	Identity:	86/335 - (25%)
Similarity:	146/335 - (43%)	Gaps:	60/335 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 VYAVNRDDGETLFGSGLNTDSQLGFQVKGNPNDPANLDVIIYPTAIKLPRVQGETDEDMRVKSMS 163
            :|....|:   :|..|.|....||.....:..:|..||.:                ...::.|:|
  Rat    93 LYTTVNDE---IFVLGTNCSGCLGVGDIQSTIEPRRLDSL----------------TGKKIASLS 138

  Fly   164 AGRA-HLVVLTQNGTIFTLGNNSYGQCGRSIIEEERYSKSALIHRISQEDICGKEDEVVQVECGQ 227
            .|.. |:|:.|.:|.:||.|:|:|.|.|...      :...|:......::..|  :|::|.||.
  Rat   139 YGSGPHIVLATTDGEVFTWGHNAYSQLGNGT------TNHGLVPCHISTNLSNK--QVIEVACGS 195

  Fly   228 DHSMFLTKKGRIYTCGWGADGQTGQGNYHTAGQ-----ITLIGGDVEKEKIVRLSCSSDCVLALN 287
            .||:.||..|.::..|:...||.|.|:  ||.|     :|   |.::.:.::.::|...|.:|:.
  Rat   196 YHSLVLTSDGEVFAWGYNNSGQVGSGS--TANQPIPRRVT---GCLQNKVVMSIACGQMCSMAVV 255

  Fly   288 EAGDAFGWGNSEYGQLDDSELAETQINIPRALKLTKSIG-KIKDVAAGGSFCMALNDQGLVYTWG 351
            :.|:.:.||.:..|||.    ..:..|.|...::....| :::.||.|.:..:.|.|:|.:|.||
  Rat   256 DTGEVYVWGYNGNGQLG----LGSSGNQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQIYAWG 316

  Fly   352 ---FGILGFGPFVEQTSKPQHLLP-PLFGRNDFSNETTVVSI-GCGVFHMGAVNSD-GDLFMWGK 410
               :|.||.|      :|.....| |:....|     .::.| .|...|..|..|. |.::|||:
  Rat   317 ANSYGQLGTG------NKSNQSYPTPVVVEKD-----RIIEIAACHSAHTSAAKSQGGHVYMWGQ 370

  Fly   411 NRFGHLGLGH 420
            .|...:.|.|
  Rat   371 CRGQSVILPH 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3862	NP_608550.1	RCC1	43..99	CDD:278826	86/335 (26%)
		RCC1_2	159..188	CDD:290274	12/29 (41%)
		RCC1	175..233	CDD:278826	16/57 (28%)
		RCC1_2	220..249	CDD:290274	10/28 (36%)
		RCC1	236..286	CDD:278826	13/54 (24%)
		RCC1	290..341	CDD:278826	12/51 (24%)
		RCC1	345..395	CDD:278826	14/54 (26%)
		RCC1_2	386..414	CDD:290274	10/29 (34%)
		RCC1	402..449	CDD:278826	7/20 (35%)
Rcbtb2	XP_038949091.1	ATS1	<141..421	CDD:227511	73/268 (27%)
		BTB_POZ_RCBTB2_CHC1L	408..524	CDD:349663
		BACK_RCBTB2	521..585	CDD:350604
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820