Protein Alignment CG3862 and RCC1

DIOPT Version :10

• Sequence 1: NP_608550.1
• Gene: CG3862 / 33261
• FlyBaseID: FBgn0031286
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_001041659.1
• Gene: RCC1 / 1104
• HGNCID: 1913
• Length: 452
• Species: Homo sapiens
• Alignment Length: 455
• Identity: 115/455 - (25%)
• Similarity: 178/455 - (39%)
• Gaps: 92/455 - (20%)

  Fly    30 KIKEYSPKTTDSHEHRVYVWGFQETGALGLQTNVKKAKERYTEMVHHPTRLQFSNNNEITDVAAG 94
            |.:..|.::..:....|...|..:.|.|||..||.:.|:  ..:|..|        .::....||
Human    52 KTRPVSHRSHSTEPGLVLTLGQGDVGQLGLGENVMERKK--PALVSIP--------EDVVQAEAG 106

  Fly    95 YGFTVYAVNRDDGETLFGSGLNTDSQLG--FQVKGNPNDPANLDVIIYPTAIKLPRVQGETDEDM 157
               .::.|.......::..|.|.:..||  ..|:|:                  ..|.|:.:...
Human   107 ---GMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGS------------------EMVPGKVELQE 150

  Fly   158 RVKSMSAGRAHLVVLTQNGTIFTLGN--NSYGQCGRSIIEEERYSKSALIHRISQEDICGKEDEV 220
            :|..:|||.:|...||.:|.:|..|:  ::.|..|  ::|.   .|.:::....|.|:     .|
Human   151 KVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIG--LLEP---MKKSMVPVQVQLDV-----PV 205

  Fly   221 VQVECGQDHSMFLTKKGRIYTCGWGADGQTGQGNYHTAGQITLIGGDVEKEKI------------ 273
            |:|..|.||.:.||..|.:||.|.|..||.|:.....|.:    ||....|::
Human   206 VKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANR----GGRQGLERLLVPKCVMLKSRG 266

  Fly   274 ----VRLS---CSSDCVLALNEAGDAFGWGNSEYGQL--DDSELAETQINIPRALKLTKS-IGKI 328
                ||..   |.:....|::..|..:|:|.|.|.||  ..:|......|:......||| :|
Human   267 SRGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVG-- 329

  Fly   329 KDVAAGGSFCMALNDQGLVYTWG---FGILGFGPFVEQTSKPQHLLPPLFGRNDFSNETTVVSIG 390
              .:.|....:.::.:|..|:.|   :|.||.|...|:.|     :|.|..|     ...|.|:.
Human   330 --FSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKS-----IPTLISR-----LPAVSSVA 382

  Fly   391 CGVFHMGAVNSDGDLFMWGKNRFGHLGLGHKKDQFFPF----KAAINGKVTKVAYGVDHTIALCK 451
            ||.....||..||.:|.||......||.|..:|.:.|.    |...|..|..|:.|..||:.|.|
Human   383 CGASVGYAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVK 447

  Fly   452  451
            Human   448  447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3862	NP_608550.1	RCC1	43..99	CDD:395335	13/55 (24%)
		ATS1	89..449	CDD:444065	100/392 (26%)
RCC1	NP_001041659.1	ATS1	60..420	CDD:444065	103/418 (25%)