DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3862 and Rcbtb2

DIOPT Version :9

Sequence 1:	NP_608550.1	Gene:	CG3862 / 33261	FlyBaseID:	FBgn0031286	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	NP_001164165.1	Gene:	Rcbtb2 / 105670	MGIID:	1917200	Length:	551	Species:	Mus musculus

Alignment Length:	351	Identity:	88/351 - (25%)
Similarity:	150/351 - (42%)	Gaps:	70/351 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 SNNNEITDVAAGYGFTVYAVNRDDGETLFGSGLNTDSQLGFQVKGNPNDPANLDVIIYPTAIKLP 147
            |..||:          :|....|:   :|..|.|....||.....:..:|..||.:
Mouse    53 SAGNEV----------LYTTVNDE---IFVLGTNCSGCLGVGDIQSTIEPRRLDSL--------- 95

  Fly   148 RVQGETDEDMRVKSMSAGRA-HLVVLTQNGTIFTLGNNSYGQCGRSIIEEERYSKSALIHRISQE 211
                   ...::.|:|.|.. |:|:.|.:|.:||.|:|:|.|.|...      :...|:......
Mouse    96 -------TGKKIASLSYGSGPHIVLATTDGEVFTWGHNAYSQLGNGT------TNHGLVPCHIST 147

  Fly   212 DICGKEDEVVQVECGQDHSMFLTKKGRIYTCGWGADGQTGQGNYHTAGQ-----ITLIGGDVEKE 271
            ::..|  :|::|.||..||:.||..|.::..|:...||.|.|:  ||.|     :|   |.::.:
Mouse   148 NLSNK--QVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGS--TANQPIPRRVT---GCLQNK 205

  Fly   272 KIVRLSCSSDCVLALNEAGDAFGWGNSEYGQLDDSELAETQINIPRALKLTKSIG-KIKDVAAGG 335
            .::.::|...|.:|:.:.|:.:.||.:..|||.    ..:..|.|...::....| :::.||.|.
Mouse   206 VVMNIACGQMCSMAVVDTGEVYVWGYNGNGQLG----LGSSGNQPTPCRVAALQGIRVQRVACGY 266

  Fly   336 SFCMALNDQGLVYTWG---FGILGFGPFVEQTSKPQHLLP-PLFGRNDFSNETTVVSI-GCGVFH 395
            :..:.|.|:|.:|.||   :|.||.|      :|.....| |:....|     .::.| .|...|
Mouse   267 AHTLVLTDEGQIYAWGANSYGQLGTG------NKSNQSYPTPVVVEKD-----RIIEIAACHSAH 320

  Fly   396 MGAVNSD-GDLFMWGKNRFGHLGLGH 420
            ..|..:. |.::|||:.|...:.|.|
Mouse   321 TSAAKTQGGHVYMWGQCRGQSVILPH 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3862	NP_608550.1	RCC1	43..99	CDD:278826	3/15 (20%)
		RCC1_2	159..188	CDD:290274	12/29 (41%)
		RCC1	175..233	CDD:278826	16/57 (28%)
		RCC1_2	220..249	CDD:290274	10/28 (36%)
		RCC1	236..286	CDD:278826	13/54 (24%)
		RCC1	290..341	CDD:278826	12/51 (24%)
		RCC1	345..395	CDD:278826	14/54 (26%)
		RCC1_2	386..414	CDD:290274	9/29 (31%)
		RCC1	402..449	CDD:278826	7/20 (35%)
Rcbtb2	NP_001164165.1	RCC1 1. /evidence=ECO:0000255	64..115		14/69 (20%)
		ATS1	<107..335	CDD:227511	67/255 (26%)
		RCC1 2. /evidence=ECO:0000255	117..169		17/59 (29%)
		RCC1 3. /evidence=ECO:0000255	171..222		14/55 (25%)
		RCC1 4. /evidence=ECO:0000255	223..274		13/54 (24%)
		RCC1 5. /evidence=ECO:0000255	276..326		16/60 (27%)
		RCC1 6. /evidence=ECO:0000255	328..382		7/19 (37%)
		BTB_POZ_RCBTB2_CHC1L	374..490	CDD:349663
		BACK_RCBTB2	487..551	CDD:350604
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820