DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3862 and LOC100536575

DIOPT Version :9

Sequence 1:	NP_608550.1	Gene:	CG3862 / 33261	FlyBaseID:	FBgn0031286	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	XP_009295984.1	Gene:	LOC100536575 / 100536575	-ID:	-	Length:	409	Species:	Danio rerio

Alignment Length:	434	Identity:	105/434 - (24%)
Similarity:	159/434 - (36%)	Gaps:	112/434 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 RYTEMVHHPTRLQFSNNNEITDVAAGYGFTVYAVNRDDGETLFGSGLNTDSQL-----GFQVKGN 128
            :||:..|   |..|     :|...|....||..|::....:.||.|.|...|:     ..|||..
Zfish     3 KYTDNRH---RFGF-----LTTFRAQKQLTVLCVDQSKSMSWFGFGFNGFGQISRADVSGQVKCK 59

  Fly   129 PNDPANLDVIIYPTAIKLPRVQGETDEDMRVKSMSAGRAHLVVLTQNGTIFTLGNNSYGQ----- 188
            .|.|    |:|.....|    .|....|.|:::..:.||.| ..||:|:...|.....|.
Zfish    60 VNSP----VLISDDECK----SGVNRSDRRIRACWSSRADL-QQTQSGSGVYLSGCVCGPSAQVC 115

  Fly   189 ----CGRSIIEEERYSKSALIHRISQEDICGKEDEVVQVECGQDHSMFLTKKGRIYTCGWGADGQ 249
                |..::|.|...:.| ...|:...:|..:::::|                      |..:.:
Zfish   116 ASQGCTDALISETHLTLS-FTDRVELWEIKPQQNQLV----------------------WKREHE 157

  Fly   250 TGQGNYHTAGQITLIGGDVE---------KEKIVRLSCSSDCVLALNEAGDAFGWGNSEYGQLDD 305
            ...  .|||....:.||.|:         |...|.|...|:..|.|...|..:.||:..:|||..
Zfish   158 LSA--EHTAALPLVSGGFVQHKPPFFHPLKLCAVSLVLGSEHALLLTADGTLYSWGSGSHGQLGH 220

  Fly   306 SELAETQINIPRALKLTKSIGKIKDVAAGGSFCMALNDQGLVYTWGF---GILGFGPFVEQTSKP 367
            ..|  |.:..|:|::....: .||.||||.....|::..|.:|.||:   |.||......:..|.
Zfish   221 GVL--TSLEDPQAVEALWGV-PIKAVAAGNWHSAAVSSGGDLYMWGWNESGQLGLPSRGLEEEKR 282

  Fly   368 Q-------------------------HLLPPLFGRNDFSNETTVVSIGCGVFHMGAVNSDGDLFM 407
            :                         ...|.|.   |.:|.:.:..|.||..|..||.|.|||:.
Zfish   283 RGNGSGNDDQPINTDGKSRTDVFISIQAFPALV---DIANMSEISRISCGSRHTAAVTSAGDLYT 344

  Fly   408 WGKNRFGHLGLG--HKKDQFFPFKAAINGKVTKVAYGVDHTIAL 449
            ||..::|.||.|  |..|:           .|.|.|...|::::
Zfish   345 WGWGQYGQLGHGTEHSTDE-----------PTPVDYFSSHSLSV 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3862	NP_608550.1	RCC1	43..99	CDD:278826	7/29 (24%)
		RCC1_2	159..188	CDD:290274	7/28 (25%)
		RCC1	175..233	CDD:278826	10/66 (15%)
		RCC1_2	220..249	CDD:290274	2/28 (7%)
		RCC1	236..286	CDD:278826	12/58 (21%)
		RCC1	290..341	CDD:278826	16/50 (32%)
		RCC1	345..395	CDD:278826	15/77 (19%)
		RCC1_2	386..414	CDD:290274	12/27 (44%)
		RCC1	402..449	CDD:278826	15/48 (31%)
LOC100536575	XP_009295984.1	RCC1_2	189..217	CDD:290274	8/27 (30%)
		RCC1	204..253	CDD:278826	16/51 (31%)
		RCC1_2	240..269	CDD:290274	11/28 (39%)
		RCC1	257..336	CDD:278826	16/81 (20%)
		RCC1_2	323..352	CDD:290274	12/28 (43%)
		RCC1	340..389	CDD:278826	15/49 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910