DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3862 and herc1

DIOPT Version :9

Sequence 1:	NP_608550.1	Gene:	CG3862 / 33261	FlyBaseID:	FBgn0031286	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	XP_017947876.1	Gene:	herc1 / 100493988	XenbaseID:	XB-GENE-1002062	Length:	4854	Species:	Xenopus tropicalis

Alignment Length:	440	Identity:	111/440 - (25%)
Similarity:	188/440 - (42%)	Gaps:	68/440 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 LAQDKSKIKEYSPKTTDSHEH-------RVYVWGFQETGALGLQTNVKKAKERYTEMVHHPTRLQ 81
            :|.|.|:... ||.:..|.|:       .|||||...:..|     |:..:|:..:....|.
Frog   346 MASDYSRTCA-SPDSIQSGENPVVSETCEVYVWGSNSSHQL-----VEGTQEKILQPKLAPC--- 401

  Fly    82 FSNNNEITDVAAGYGFTVYAVNRDDGETLFGSGLNTDSQLGFQVKGNPNDPANLDVIIYPTAIKL 146
            ||   :...:.||. :..:.::.|......|.|  :..:||.   |:.|:.:.|..:.:.....:
Frog   402 FS---DAQTIEAGQ-YCTFVISTDGSVRACGKG--SYGRLGL---GDSNNQSTLKKLTFEPHRSI 457

  Fly   147 PRVQGETDEDMRVKSMSAGRAHLVVLTQNGTIFTLGNNSYGQCGRSIIEEERYSKSALIHRISQE 211
            .:|......|          .|.:..|..|.:|:.|:..||:.|......::|.|      :.|.
Frog   458 KKVSSSKGSD----------GHTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPK------LIQG 506

  Fly   212 DICGKEDEVVQVECGQDHSMFLTKKGRIYTCGWGADGQTGQGNYHTAGQITLIGGDVEKEKIVRL 276
            .:.||  .||.|..|..||..:|:.|.:||.|.|..|:.|.|:.::....||: .|:  ..:..:
Frog   507 TLQGK--VVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLV-KDI--SNVGEV 566

  Fly   277 SCSSDCVLALNEAGD---AFGWG-NSEYGQLDDSELAETQINIPRALKLTKSIGKIKDVAAGGSF 337
            ||.|...:||::.|.   :||.| |.:.|..|.:.:.:     |:.::..:.:...| |.||...
Frog   567 SCGSSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYK-----PKVVEALQGMFTRK-VCAGSQS 625

  Fly   338 CMALNDQGLVYTWGFG-ILGFGPFVEQTSKPQHLLPPLFGRNDFSNETTVVSIGCGVFHMGAVNS 401
            .:||...|.||.||.| .||.|     :|:...|.|.|.   :....|.:|.|..|..|..|::.
Frog   626 SLALTSTGQVYAWGCGACLGCG-----SSEATALRPKLI---EELAATRIVDISIGDSHCLALSH 682

  Fly   402 DGDLFMWGKNRFGHLGLGHKKDQFFPFK--AAING-KVTKVAYGVDHTIA 448
            |.:::.||.|..|..|.|:........|  :.::| .:.:::.|..|::|
Frog   683 DNEVYAWGNNSMGQCGQGNSTGPITKPKKVSGLDGVAIQQISAGTSHSLA 732

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3862	NP_608550.1	RCC1	43..99	CDD:278826	14/62 (23%)
		RCC1_2	159..188	CDD:290274	6/28 (21%)
		RCC1	175..233	CDD:278826	17/57 (30%)
		RCC1_2	220..249	CDD:290274	12/28 (43%)
		RCC1	236..286	CDD:278826	14/49 (29%)
		RCC1	290..341	CDD:278826	12/54 (22%)
		RCC1	345..395	CDD:278826	17/50 (34%)
		RCC1_2	386..414	CDD:290274	9/27 (33%)
		RCC1	402..449	CDD:278826	12/50 (24%)
herc1	XP_017947876.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920