DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3862 and herc3

DIOPT Version :9

Sequence 1:	NP_608550.1	Gene:	CG3862 / 33261	FlyBaseID:	FBgn0031286	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	XP_002938676.3	Gene:	herc3 / 100488790	XenbaseID:	XB-GENE-968537	Length:	1050	Species:	Xenopus tropicalis

Alignment Length:	290	Identity:	89/290 - (30%)
Similarity:	135/290 - (46%)	Gaps:	55/290 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   182 GNNSYGQCG-----RSIIEEE---RYSKSALIHRISQEDICGKEDEVVQVECGQDHSMFLTKKGR 238
            |::::||.|     :..:.:.   |:|.:|          |.||     |.||..|::||.:.|:
Frog     5 GHSTFGQLGNGHSFQGSVSDPCVCRFSLAA----------CVKE-----VACGGKHTLFLLEDGQ 54

  Fly   239 IYTCGWGADGQTGQGNYHT-AGQITLIGGDVEKEKIVRLSCSSDCVLALNEAGDAFGWGNSEYGQ 302
            :|:|||..:||.|..:..| ..|:|.:    .:|.|..::|.....|||:..|..:.||:...||
Frog    55 VYSCGWNGEGQLGHDHEGTDPVQVTTL----TEEHITHIACGQSHNLALSYQGQLYSWGSGNDGQ 115

  Fly   303 LDDSELAETQINIPRALKLTKSIGKIKDVAAGGSFCMALNDQGLVYTWG---FGILGFG-PFVEQ 363
            |..:.: |....|||.:|.... .||:.|:.|...||||.|.|.::|||   .|.||.| .|:.|
Frog   116 LGHATV-EHSSRIPRIIKKLNQ-QKIQQVSCGNDHCMALGDDGQLFTWGQNLHGQLGLGNGFLSQ 178

  Fly   364 TSKPQHL-----LPPLFGRNDFSNETTVVSIGCGVFHMGAVNSDGDLFMWGKNRFGHLGLGHKKD 423
            :| ||.:     :|             :..:..|..|..|::..|.:|.||.|..|.|||..:|.
Frog   179 SS-PQRVKSLEGIP-------------LAQVTAGGSHSFALSLSGAVFGWGNNSAGQLGLNDEKV 229

  Fly   424 QFFP--FKAAINGKVTKVAYGVDHTIALCK 451
            :..|  .|.....||..::.|.:||..|.|
Frog   230 RETPCHVKPLRTHKVIYISCGEEHTAILTK 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3862	NP_608550.1	RCC1	43..99	CDD:278826
		RCC1_2	159..188	CDD:290274	1/5 (20%)
		RCC1	175..233	CDD:278826	14/58 (24%)
		RCC1_2	220..249	CDD:290274	11/28 (39%)
		RCC1	236..286	CDD:278826	15/50 (30%)
		RCC1	290..341	CDD:278826	17/50 (34%)
		RCC1	345..395	CDD:278826	15/58 (26%)
		RCC1_2	386..414	CDD:290274	8/27 (30%)
		RCC1	402..449	CDD:278826	17/48 (35%)
herc3	XP_002938676.3	RCC1	3..49	CDD:395335	14/58 (24%)
		ATS1	44..353	CDD:227511	76/236 (32%)
		HECTc	702..1048	CDD:238033
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920