DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3862 and herc6

DIOPT Version :9

Sequence 1:	NP_608550.1	Gene:	CG3862 / 33261	FlyBaseID:	FBgn0031286	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	XP_031759089.1	Gene:	herc6 / 100487734	XenbaseID:	XB-GENE-968556	Length:	1030	Species:	Xenopus tropicalis

Alignment Length:	301	Identity:	101/301 - (33%)
Similarity:	148/301 - (49%)	Gaps:	39/301 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   159 VKSMSAGRAHLVVLTQNGTIFTLGNNSYGQCGRSIIEEERYSKSALIHRISQEDICGKEDEVVQV 223
            |:.:|.|..|.:.|.::||:.:.|.|.|||.||.       |.::.|.:||..:    ...:|.:
Frog    36 VQKVSCGEKHTLYLLEDGTLLSCGQNPYGQLGRK-------SNNSSIEQISSLE----AQTIVDI 89

  Fly   224 ECGQDHSMFLTKKGRIYTCGWGADGQTGQGNY----HTAGQITLIGGDVEKEKIVRLSCSSDCVL 284
            .||.:||:.::.:|.||:.|.|::||.|.||.    .|..:||    .:...||:::||.:...|
Frog    90 SCGTNHSVAVSDEGSIYSWGDGSEGQLGTGNLSSRNFTPKKIT----GLFNTKIIQISCGNFHSL 150

  Fly   285 ALNEAGDAFGWGNSEYGQLDDSELAETQIN--IPRALKLTKSIGKIKDVAAGGSFCMALNDQGLV 347
            ||:|.|..|.||.::.|||.   |....||  .|:.:|..|.|..:: |.||||...||:..|.|
Frog   151 ALSEDGRVFSWGQNKCGQLG---LGSQIINQATPQLVKSLKGIPLVQ-VTAGGSQSFALSMSGTV 211

  Fly   348 YTWG---FGILGF--GPFVEQTSKPQHLLPPLFGRNDFSNETTVVSIGCGVFHMGAVNSDGDLFM 407
            :.||   .|.|||  .|....|.|| |.:..|  ||     ..|..|.||..|...::.||.::.
Frog   212 FAWGKNNAGQLGFKSDPMKAGTFKP-HAVNSL--RN-----LGVAYISCGEEHTAVLSKDGSVYT 268

  Fly   408 WGKNRFGHLGLGHKKDQFFPFKAA-INGKVTKVAYGVDHTI 447
            :|.:..|.||.........|.|.. ..|:|::||.|..||:
Frog   269 FGDDTHGQLGQNSGNQTSVPQKIEDYAGQVSQVACGRYHTL 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3862	NP_608550.1	RCC1	43..99	CDD:278826
		RCC1_2	159..188	CDD:290274	10/28 (36%)
		RCC1	175..233	CDD:278826	18/57 (32%)
		RCC1_2	220..249	CDD:290274	10/28 (36%)
		RCC1	236..286	CDD:278826	18/53 (34%)
		RCC1	290..341	CDD:278826	19/52 (37%)
		RCC1	345..395	CDD:278826	20/54 (37%)
		RCC1_2	386..414	CDD:290274	8/27 (30%)
		RCC1	402..449	CDD:278826	15/47 (32%)
herc6	XP_031759089.1	ATS1	2..373	CDD:227511	101/301 (34%)
		HUL4	324..1021	CDD:227354
		HECTc	684..1028	CDD:238033
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010