DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3862 and nek9

DIOPT Version :9

Sequence 1:	NP_608550.1	Gene:	CG3862 / 33261	FlyBaseID:	FBgn0031286	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	XP_021323186.1	Gene:	nek9 / 100334361	-ID:	-	Length:	921	Species:	Danio rerio

Alignment Length:	463	Identity:	105/463 - (22%)
Similarity:	170/463 - (36%)	Gaps:	126/463 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 SKIKEYSPKTTDSHEHRVYVWGFQETGALGLQTNVKKAKERYTEMVHHPTRL-QFSNNNEITDVA 92
            |.:.|.|.....:....||.||    |.            ::|     |.:| .|...:....|.
Zfish   321 STVTETSVAVVTTRSREVYFWG----GG------------KFT-----PQKLDMFKGGSSAQHVC 364

  Fly    93 AG-YGFTVYAVNRD--------DGETLFGSGLNTDSQLGFQVKGNPNDPANLDVIIYPTAIKLPR 148
            || ..|.|..|.::        .|..:.|       |||...:.:...|..::           |
Zfish   365 AGETHFAVVTVEKELYTWASVQGGAKMVG-------QLGHGDQASYRQPRRVE-----------R 411

  Fly   149 VQGETDEDMRVKSMSAGRAHLVVLTQNGTIFTLGNNSYG------QCGRSIIEE---ERYSKSAL 204
            :||:.     ::.:| |......:|....|:..|::.||      :.|..::|.   |.:::.|
Zfish   412 LQGKA-----IRQVSXGADFTACVTDEDQIYMFGSDYYGCVGVENELGMEVLEPVLLEFFTERA- 470

  Fly   205 IHRISQEDICGKEDEVVQVECGQDHSMFLTKKGRIYTCGWGADGQTG---QGNYHTAGQITLIGG 266
                           |.||.||.:|.:.||:...:|..|.|..|:.|   :.::.:..|:.:..|
Zfish   471 ---------------VRQVSCGDNHVLALTQSRELYAWGCGEHGRLGLDCEDDFSSPMQVEVPQG 520

  Fly   267 DVEKEKIVRLSCSSDCVLALNEAGDAFGWGNSEYGQLD--------DSELAETQINIP--RALKL 321
            .|    |..:.|.||....|.|:|.....||:|:.:|.        .:...|....||  ..|.|
Zfish   521 AV----IDSVYCGSDGTFFLTESGKVLACGNNEFNKLGLNQGITGIKNHPGEGYQGIPYTTTLTL 581

  Fly   322 TKSIG--KIKDVAAGGSFCMALNDQGLVYTWG---FGILGFGPFVEQTSKPQHLLPPLFGRNDFS 381
            .|.:.  ||:.:|.|.:...|::::|.:.|:|   ||.||...| ::....|.|:.|..|:
Zfish   582 VKLLSRFKIQFLAPGKTHTAAIDERGRLMTFGCNKFGQLGVKDF-KKHQGVQILVGPFGGK---- 641

  Fly   382 NETTVVSIGCGVFHMGAVNSDGDLFMWGKNRFGHLGLGHKKDQFFPFKAAINGKVTKVAYGVDHT 446
               .|..:.||.....|...|..:|.||....|.||:...|                 .:|.:..
Zfish   642 ---IVTKVSCGDGFTIAATEDNQIFAWGNAGNGRLGMPADK-----------------GFGSEVC 686

  Fly   447 IALCKPFF 454
            .||.:|.|
Zfish   687 PALPRPIF 694

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3862	NP_608550.1	RCC1	43..99	CDD:278826	13/57 (23%)
		RCC1_2	159..188	CDD:290274	7/34 (21%)
		RCC1	175..233	CDD:278826	14/66 (21%)
		RCC1_2	220..249	CDD:290274	11/28 (39%)
		RCC1	236..286	CDD:278826	12/52 (23%)
		RCC1	290..341	CDD:278826	15/62 (24%)
		RCC1	345..395	CDD:278826	15/52 (29%)
		RCC1_2	386..414	CDD:290274	8/27 (30%)
		RCC1	402..449	CDD:278826	9/46 (20%)
nek9	XP_021323186.1	STKc_Nek9	40..297	CDD:270860
nek9	XP_021323186.1	RCC1	<347..657	CDD:332518	84/365 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010