DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3862 and als2b

DIOPT Version :9

Sequence 1:	NP_608550.1	Gene:	CG3862 / 33261	FlyBaseID:	FBgn0031286	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	XP_009300450.1	Gene:	als2b / 100318899	ZFINID:	ZDB-GENE-080929-1	Length:	1706	Species:	Danio rerio

Alignment Length:	166	Identity:	39/166 - (23%)
Similarity:	71/166 - (42%)	Gaps:	42/166 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   145 KLPRVQGETD----------EDMRVKSMSAGRAHLVVLTQNGTIFTLGNNSYGQC---GRSIIEE 196
            :||..|.:|.          .:.||..::||.||..|:|::|.:...|.|.:|||   |.|:|
Zfish    64 ELPWKQNQTSSAEPILEAVLSEQRVVFVAAGSAHSGVVTEDGGVHMWGENVHGQCGLLGLSVI-- 126

  Fly   197 ERYSKSALIHRISQEDICGKEDEVVQVECGQDHSMFLTKKGRIYTCGWGADGQTG---------- 251
               .....:..:..|....:..::::|.||..|::.|:.|..::  .||:..|.|
Zfish   127 ---PNPTPVGVLDSEATPPQTVKILEVACGDQHTLALSAKHEVW--AWGSGCQLGLNTSTFPVWK 186

  Fly   252 -QGNYHTAGQITLIGGDVEKEKIVRLSCSSDCVLAL 286
             |...|.:|:           .:::::|.|...:||
Zfish   187 PQKVDHLSGR-----------HVLQVACGSAHSVAL 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3862	NP_608550.1	RCC1	43..99	CDD:278826
		RCC1_2	159..188	CDD:290274	10/28 (36%)
		RCC1	175..233	CDD:278826	14/60 (23%)
		RCC1_2	220..249	CDD:290274	8/28 (29%)
		RCC1	236..286	CDD:278826	10/60 (17%)
		RCC1	290..341	CDD:278826
		RCC1	345..395	CDD:278826
		RCC1_2	386..414	CDD:290274
		RCC1	402..449	CDD:278826
als2b	XP_009300450.1	RCC1_2	88..117	CDD:290274	10/28 (36%)
		RCC1	104..160	CDD:278826	14/60 (23%)
		RCC1	165..211	CDD:278826	9/58 (16%)
		RCC1	567..614	CDD:278826
		RCC1	619..665	CDD:278826
		PH_alsin	952..1065	CDD:241423
		COG4642	1085..1290	CDD:226989
		MORN	1104..1124	CDD:280628
		MORN	1153..1173	CDD:197832
		VPS9	1603..1702	CDD:280383
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900