DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3862 and herc3

DIOPT Version :9

Sequence 1:	NP_608550.1	Gene:	CG3862 / 33261	FlyBaseID:	FBgn0031286	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	NP_001139096.1	Gene:	herc3 / 100003587	ZFINID:	ZDB-GENE-090313-139	Length:	1046	Species:	Danio rerio

Alignment Length:	236	Identity:	82/236 - (34%)
Similarity:	114/236 - (48%)	Gaps:	20/236 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   222 QVECGQDHSMFLTKKGRIYTCGWGADGQTGQGNYHTAGQITLIGGDVEKEKIVRLSCSSDCVLAL 286
            :|.||..||:||...|.:||||..:.||.|   :...|....:.|.::.:||..:||.....||:
Zfish    38 EVACGNQHSLFLLHDGSVYTCGSNSCGQLG---HDKGGSRPELVGALDAQKISGVSCGQAHSLAV 99

  Fly   287 NEAGDAFGWGNSEYGQLDDSELAETQINIPRAL-KLTKSIGKIKDVAAGGSFCMALNDQGLVYTW 350
            ||.|..|.||..:.||| ....||..:.:||.: ||.:.  :|..|..|...|:||:..|.::.|
Zfish   100 NEQGQVFAWGAGDGGQL-GLGTAEEAVRVPRLIKKLCEH--RISQVMCGNHHCIALSKDGQLFVW 161

  Fly   351 G---FGILGFGPFVEQTSKPQHLLPPLFGRNDFSNETTVVSIGCGVFHMGAVNSDGDLFMWGKNR 412
            |   .|.||.|.....|..||. |..|.|       ..:..|..|..|..|::..|.:|.||||.
Zfish   162 GENSSGQLGLGKGEPSTLSPQP-LKSLCG-------IPLTQISAGGDHSFALSFSGAVFGWGKNS 218

  Fly   413 FGHLGLGHKKDQFFP--FKAAINGKVTKVAYGVDHTIALCK 451
            .|.|||..::|:..|  .|...:.||..::.|.:||.||.|
Zfish   219 AGQLGLNDEQDRAVPCHIKFLRSQKVVYISCGEEHTAALTK 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3862	NP_608550.1	RCC1	43..99	CDD:278826
		RCC1_2	159..188	CDD:290274
		RCC1	175..233	CDD:278826	5/10 (50%)
		RCC1_2	220..249	CDD:290274	12/26 (46%)
		RCC1	236..286	CDD:278826	15/49 (31%)
		RCC1	290..341	CDD:278826	17/51 (33%)
		RCC1	345..395	CDD:278826	15/52 (29%)
		RCC1_2	386..414	CDD:290274	10/27 (37%)
		RCC1	402..449	CDD:278826	18/48 (38%)
herc3	NP_001139096.1	RCC1	4..49	CDD:278826	5/10 (50%)
		RCC1_2	37..65	CDD:290274	12/26 (46%)
		RCC1	52..99	CDD:278826	15/49 (31%)
		RCC1	103..152	CDD:278826	17/51 (33%)
		RCC1	155..205	CDD:278826	16/57 (28%)
		RCC1	208..257	CDD:278826	18/48 (38%)
		RCC1	260..308	CDD:278826	82/236 (35%)
		RCC1	314..374	CDD:278826
		HECTc	699..1044	CDD:238033
		HECTc	723..1043	CDD:214523
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920