DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3662 and itm2bb

DIOPT Version :9

Sequence 1:	NP_001162847.1	Gene:	CG3662 / 33260	FlyBaseID:	FBgn0031285	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_998141.1	Gene:	itm2bb / 406248	ZFINID:	ZDB-GENE-040426-2139	Length:	254	Species:	Danio rerio

Alignment Length:	264	Identity:	68/264 - (25%)
Similarity:	112/264 - (42%)	Gaps:	45/264 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 DNEADAESMVFNRPQHH----CIKSFLLFLIAVVVMLLG-VLGGWTLYRVYAPSHSSMRYHALCE 102
            :.|.|.|::|..|.|..    |      |.:.:.::|.| |:.|..|||.|......:   .:|.
Zfish    22 NEEQDPEAVVLVRHQSRVWCWC------FCLGLTLVLSGVVVAGAYLYRYYVLERDQV---FICG 77

  Fly   103 IPYPEDSMEMARVYPRTVEPFALNWRSLLPELAQPMPNSGSLDES-HFREDIELDGDSDDEGYAR 166
            :.|.|             |.:.|| ..:.||:..|:   ..::|: .|.||.|::       ...
Zfish    78 LKYYE-------------EDYELN-EEVDPEIGAPL---RLIEENVSFFEDDEVE-------LIS 118

  Fly   167 VDVPDFKDGRRGRFMHDFKENQSAIIDTTTGRCFIMPLDRDTTLPPTSFVDLIKKMSTGYYNIDT 231
            |.||:|||......:|||....:|.:|....:|:|:.|:....:||..|.:.:..:..|.|...|
Zfish   119 VPVPEFKDSDPAGILHDFTMKLTAYLDLNLDKCYIITLNTSVVMPPRDFQEFLVNIKEGMYLPQT 183

  Fly   232 ERVRRQMRVVMPRITDVSLISERIANECFDMKVYMMEK--FVSGVSKRSADPLPESAKYAEFMGK 294
            ..:..:| :|..::.|.|.:...|.|.|.|...|.:::  .:.|:.||.|   ....|...|..|
Zfish   184 YLIHEEM-MVTEKLDDTSDLGYYINNLCKDKDTYRLQRRDTILGMQKREA---LNCHKIRHFENK 244

  Fly   295 GVIE 298
            .|:|
Zfish   245 FVVE 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3662	NP_001162847.1	BRICHOS	172..267	CDD:198107	26/94 (28%)
itm2bb	NP_998141.1	BRICHOS	124..218	CDD:198107	26/94 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594623
Domainoid	1	1.000	47	1.000	Domainoid score	I11984
eggNOG	1	0.900	-	-		E1_KOG4681
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	67	1.000	Inparanoid score	I5345
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1322680at2759
OrthoFinder	1	1.000	-	-		FOG0001782
OrthoInspector	1	1.000	-	-		oto40733
orthoMCL	1	0.900	-	-		OOG6_108495
Panther	1	1.100	-	-	O	PTHR10962
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R17352
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.790