DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3662 and Itm2c

DIOPT Version :9

Sequence 1:	NP_001162847.1	Gene:	CG3662 / 33260	FlyBaseID:	FBgn0031285	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_001009674.1	Gene:	Itm2c / 301575	RGDID:	1309503	Length:	269	Species:	Rattus norvegicus

Alignment Length:	244	Identity:	54/244 - (22%)
Similarity:	93/244 - (38%)	Gaps:	61/244 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 RPQHH-----------CIKSFLLFLIAVVVMLLG-VLGGWTLYRVYAPSHSSMRYHALCEIPYPE 107
            ||..|           |..|     :.:||:|:| |.....:||.:..:..:......|.:.| |
  Rat    45 RPPRHRSRKGGSVGGVCYLS-----MGMVVLLMGLVFASVYIYRYFFLAQLARDNFFHCGVLY-E 103

  Fly   108 DSMEMARVYPRTVEPFALNWRSLLPELAQPMPNSGSLDESHFREDIELDGDSD---DEGYARVD- 168
            ||:                                   .|..|..:||:.|..   :|.|.|::
  Rat   104 DSL-----------------------------------SSQIRTRLELEEDVKIYLEENYERINV 133

  Fly   169 -VPDFKDGRRGRFMHDFKENQSAIIDTTTGRCFIMPLDRDTTLPPTSFVDLIKKMSTGYYNIDTE 232
             ||.|..|.....:|||:...:|..|.:..:|:::.|:....|||.:|.:|:..:..|.|...|.
  Rat   134 PVPQFGGGDPADIIHDFQRGLTAYHDISLDKCYVIELNTTIVLPPRNFWELLMNVKRGTYLPQTY 198

  Fly   233 RVRRQMRVVMPRITDVSLISERIANECFDMKVYMMEKFVS--GVSKRSA 279
            .::.:| ||...:.|...:...|.:.|.....|.:.:..:  .::||.|
  Rat   199 IIQEEM-VVTEHVRDKEALGSFIYHLCNGKDTYRLRRRATRRRINKRGA 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3662	NP_001162847.1	BRICHOS	172..267	CDD:198107	24/94 (26%)
Itm2c	NP_001009674.1	BRICHOS	138..230	CDD:198107	23/92 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352680
Domainoid	1	1.000	51	1.000	Domainoid score	I11269
eggNOG	1	0.900	-	-		E1_KOG4681
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	71	1.000	Inparanoid score	I5209
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1322680at2759
OrthoFinder	1	1.000	-	-		FOG0001782
OrthoInspector	1	1.000	-	-		otm45267
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10962
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.900