DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3662 and Itm2a

DIOPT Version :9

Sequence 1:	NP_001162847.1	Gene:	CG3662 / 33260	FlyBaseID:	FBgn0031285	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_032435.2	Gene:	Itm2a / 16431	MGIID:	107706	Length:	263	Species:	Mus musculus

Alignment Length:	238	Identity:	63/238 - (26%)
Similarity:	107/238 - (44%)	Gaps:	38/238 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 LLFLIAVVVMLLG-VLGGWTLYRVYAPSHSSMRYHA-LCEIPYPEDSMEMARVYPRTVEPFALNW 127
            :|.|:.:..:|.| ::||..:|:.:.|  .|..||. :|..    ||.:.....|.. ||:.|
Mouse    54 MLTLLGLSFILAGLIVGGACIYKYFMP--KSTIYHGEMCFF----DSEDPVNSIPGG-EPYFL-- 109

  Fly   128 RSLLPELAQPMPNSGSLDESHFREDIELDGDSDDEGYARVDVPDFKDGRRGRFMHDFKENQSAII 192
                     |:     .:|:..|||       |:.....|.||.|.|......:|||::..:|.:
Mouse   110 ---------PV-----TEEADIRED-------DNIAIIDVPVPSFSDSDPAAIIHDFEKGMTAYL 153

  Fly   193 DTTTGRCFIMPLDRDTTLPPTSFVDLIKKMSTGYYNIDTERVRRQMRVVMPRITDVSLISERIAN 257
            |...|.|::|||:....:.|.:.|:|..|:::|.|...|..||..: |.:..|.|||.:...|..
Mouse   154 DLLLGNCYLMPLNTSIVMTPKNLVELFGKLASGKYLPHTYVVREDL-VAVEEIRDVSNLGIFIYQ 217

  Fly   258 ECFDMKVYMMEK--FVSGVSKRSADPLPESAKYAEFMGKGVIE 298
            .|.:.|.:.:.:  .:.|.:||:.|   :..|...|..:.::|
Mouse   218 LCNNRKSFRLRRRDLLLGFNKRAID---KCWKIRHFPNEFIVE 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3662	NP_001162847.1	BRICHOS	172..267	CDD:198107	29/94 (31%)
Itm2a	NP_032435.2	BRICHOS	133..225	CDD:198107	29/92 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849070
Domainoid	1	1.000	51	1.000	Domainoid score	I11483
eggNOG	1	0.900	-	-		E1_KOG4681
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	66	1.000	Inparanoid score	I5342
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1322680at2759
OrthoFinder	1	1.000	-	-		FOG0001782
OrthoInspector	1	1.000	-	-		otm43193
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10962
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3365
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.890