| Sequence 1: | NP_001258898.1 | Gene: | HSP90AB1 / 3326 | HGNCID: | 5258 | Length: | 724 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_651601.1 | Gene: | Gp93 / 43354 | FlyBaseID: | FBgn0039562 | Length: | 787 | Species: | Drosophila melanogaster |
| Alignment Length: | 734 | Identity: | 336/734 - (45%) |
|---|---|---|---|
| Similarity: | 489/734 - (66%) | Gaps: | 36/734 - (4%) |
- Green bases have known domain annotations that are detailed below.
|
Human 10 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKID 74
Human 75 IIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQ-----AGADIS-MIGQFGVGF 133
Human 134 YSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRAD-HGEPIGRGTKVILHLKEDQTEYLEERR 197
Human 198 VKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSG 262
Human 263 KDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQL 327
Human 328 EFRALLFIPRRAPFDLFEN-KKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNIS 391
Human 392 REMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLR 456
Human 457 YHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYC 521
Human 522 VQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEI-LDKKVEKVTISNRLV 585
Human 586 SSPCCIVTSTYGWTANMERIMKAQALR---DNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKN 647
Human 648 DKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGI--------DEDEVAAEEPNAAV 704
Human 705 PDEIPPLEGDEDASRMEEV 723 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| HSP90AB1 | NP_001258898.1 | Interaction with TP53. /evidence=ECO:0000269|PubMed:15358771 | 2..527 | 261/524 (50%) | |
| Interaction with BIRC2. /evidence=ECO:0000269|PubMed:25486457 | 2..214 | 113/210 (54%) | |||
| Interaction with NR3C1. /evidence=ECO:0000250|UniProtKB:P11499 | 9..231 | 117/227 (52%) | |||
| PTZ00272 | 14..724 | CDD:240341 | 335/730 (46%) | ||
| Interaction with AHSA1. /evidence=ECO:0000269|PubMed:25486457 | 215..552 | 160/337 (47%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 222..270 | 16/47 (34%) | |||
| Interaction with NR3C1. /evidence=ECO:0000250|UniProtKB:P11499 | 264..608 | 169/345 (49%) | |||
| Interaction with NR1D1. /evidence=ECO:0000250|UniProtKB:P11499 | 620..723 | 35/110 (32%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 696..724 | 5/28 (18%) | |||
| TPR repeat-binding | 720..724 | 1/4 (25%) | |||
| Gp93 | NP_651601.1 | PRK05218 | 74..745 | CDD:235366 | 325/686 (47%) |
| HATPase_c | 97..216 | CDD:238030 | 69/118 (58%) | ||
| HSP90 | 257..748 | CDD:278607 | 226/505 (45%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG0326 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D174605at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000295 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 1 | 0.900 | - | - | OOG6_100204 | |
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X234 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 6 | 5.720 | |||||