DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Clp and Zc3h6

DIOPT Version :9

Sequence 1:	NP_477156.1	Gene:	Clp / 33259	FlyBaseID:	FBgn0015621	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	NP_848491.2	Gene:	Zc3h6 / 78751	MGIID:	1926001	Length:	1177	Species:	Mus musculus

Alignment Length:	153	Identity:	39/153 - (25%)
Similarity:	55/153 - (35%)	Gaps:	52/153 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 PLPFYGMD----------KSIAAVCNFITRNGQECDKGSACPFRHIRGDRTIVCKHWLRGLCKKG 81
            |..|.|||          |.......||.::..| .||..            :||::|.|.|.||
Mouse   236 PYVFSGMDDFQEYSKPGKKWKVMTQEFINQHTVE-HKGKQ------------ICKYFLEGRCIKG 287

  Fly    82 DQCEFLHEYDMTKMPECYFYSRFNACHNKECPFLHIDPQSKVKDCPWYKRGFCRHGPHCRHQHLR 146
            |.|:|.|:.::.|..|.                           |.:|.:|:|..|.:|.:.| .
Mouse   288 DHCKFNHDAELEKKKEV---------------------------CKYYLQGYCTKGENCIYMH-S 324

  Fly   147 RVLCMDYLAGF-CPEGPSCKHMH 168
            ...|..|.:|. |.:|..||..|
Mouse   325 EFPCKFYHSGAKCYQGDKCKFSH 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Clp	NP_477156.1	YTH1	12..175	CDD:227416	39/153 (25%)
Clp	NP_477156.1	ZnF_C3H1	66..90	CDD:214632	11/23 (48%)
Zc3h6	NP_848491.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..137
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	179..206
		ZnF_C3H1	274..295	CDD:214632	10/32 (31%)
		ZnF_C3H1	301..325	CDD:214632	8/51 (16%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	383..416
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	446..587
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	622..654
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	670..767
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	780..826
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	942..988
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1043..1101
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1132..1162
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810