Protein Alignment Clp and Cpsf4

DIOPT Version :9

• Sequence 1: NP_477156.1
• Gene: Clp / 33259
• FlyBaseID: FBgn0015621
• Length: 296
• Species: Drosophila melanogaster
• Sequence 2: NP_001361645.1
• Gene: Cpsf4 / 54188
• MGIID: 1861602
• Length: 269
• Species: Mus musculus
• Alignment Length: 308
• Identity: 160/308 - (51%)
• Similarity: 194/308 - (62%)
• Gaps: 55/308 - (17%)

  Fly     1 MDILLANVSGLQFKAERDLIEQVGAIPLPFYGMDKSIAAVCNFITRNGQECDKGSACPFRHIRGD 65
            |..::|:|..::|..|..:.:|:||.||||.|||||.||||.|..:  ..|.||..||||||.|:
Mouse     1 MQEIIASVDHIKFDLEIAVEQQLGAQPLPFPGMDKSGAAVCEFFLK--AACGKGGMCPFRHISGE 63

  Fly    66 RTIVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSRFNACHNKECPFLHIDPQSKVKDCPWYK 130
            :|:||||||||||||||||||||||||||||||||||:|..|.|||||||||||:||:||||||.
Mouse    64 KTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSKFGECSNKECPFLHIDPESKIKDCPWYD 128

  Fly   131 RGFCRHGPHCRHQHLRRVLCMDYLAGFCPEGPSCKHMHPHFEL-------PPLAEL----GKDQL 184
            ||||:|||.|||:|.|||:|::||.||||||||||.|||.|||       |||.:.    .|...
Mouse   129 RGFCKHGPLCRHRHTRRVICVNYLVGFCPEGPSCKFMHPRFELPMGTTEQPPLPQQTQPPTKQSN 193

  Fly   185 HKKLPTCHYCGELGHKANS-----CKQYVGSLEHRNNINAMDHSGGHSGGYSGHSGHIEGADDMQ 244
            :..|.......:|..:.:|     ..|.:|.::.:|:      |.|:.|
Mouse   194 NPPLQRSSSLIQLTSQNSSPNQQRAPQVIGVMQSQNS------SAGNRG---------------- 236

  Fly   245 SNHHSQPHGPGFVKVPTPLEEITCYKCGNKGHYANKCPKGHLAFLSNQ 292
                           |.|||::||||||.||||||:|.||||||||.|
Mouse   237 ---------------PRPLEQVTCYKCGEKGHYANRCTKGHLAFLSGQ 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Clp	NP_477156.1	YTH1	12..175	CDD:227416	118/169 (70%)
		ZnF_C3H1	66..90	CDD:214632	21/23 (91%)
Cpsf4	NP_001361645.1	YTH1	<25..211	CDD:227416	120/187 (64%)
		COG5222	<198..>258	CDD:227547	24/96 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830969
Domainoid	1	1.000	45	1.000	Domainoid score	I12172
eggNOG	1	0.900	-	-		E1_COG5084
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38216
Inparanoid	1	1.050	238	1.000	Inparanoid score	I3366
Isobase	1	0.950	-	0	Normalized mean entropy	S731
OMA	1	1.010	-	-		QHG49855
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002750
OrthoInspector	1	1.000	-	-		oto91900
orthoMCL	1	0.900	-	-		OOG6_103251
Panther	1	1.100	-	-	LDO	PTHR23102
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2013
SonicParanoid	1	1.000	-	-		X2133
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740