DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Clp and T26A8.4

DIOPT Version :9

Sequence 1:	NP_477156.1	Gene:	Clp / 33259	FlyBaseID:	FBgn0015621	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	NP_501435.1	Gene:	T26A8.4 / 177643	WormBaseID:	WBGene00020827	Length:	574	Species:	Caenorhabditis elegans

Alignment Length:	184	Identity:	47/184 - (25%)
Similarity:	69/184 - (37%)	Gaps:	52/184 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 QSKVKDCPWYKRGFCRHGPHCRHQH-----LRR-VLCMDYLAGFCPEGPSCKHMHPHFELPPLAE 178
            |::.:.|.:::.|:||.|.:|.:.|     ||| |||..|...||.:|..|..:|..|   |...
Worm   165 QTEHQICKFFREGYCRDGDNCLYSHQAEDSLRRPVLCNFYANSFCKKGLQCLMLHGEF---PCKS 226

  Fly   179 LGKDQLH------KKLPTCHYCGEL------------GHKANSCKQYVGSLEHRNN--INAMDHS 223
            ..|.|.:      ..:|...|...:            .|:|...:.|      |.|  .||...:
Worm   227 FHKGQCNHDPCRFSHVPLTDYTRPIIEKILADEEARQAHQAQQAQTY------RQNPVANAAAAA 285

  Fly   224 --------------GG--HSGGYSGHSGHIEGADDMQSNHHSQPHGPGFVKVPT 261
                          ||  .:|....|:..:..|...|::|.||...|..| |||
Worm   286 AAAQVMPRRRVLLPGGPNMNGSSPPHATPVIHAPIPQASHPSQLPPPAVV-VPT 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Clp	NP_477156.1	YTH1	12..175	CDD:227416	21/60 (35%)
Clp	NP_477156.1	ZnF_C3H1	66..90	CDD:214632
T26A8.4	NP_501435.1	ZnF_C3H1	168..189	CDD:214632	6/20 (30%)
		ZnF_C3H1	196..221	CDD:214632	11/24 (46%)
		PHA03160	<347..437	CDD:165431
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810