DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PGAP2 and PGAP2

DIOPT Version :9

Sequence 1:	NP_608548.1	Gene:	PGAP2 / 33258	FlyBaseID:	FBgn0031284	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	XP_011518292.2	Gene:	PGAP2 / 27315	HGNCID:	17893	Length:	391	Species:	Homo sapiens

Alignment Length:	243	Identity:	109/243 - (44%)
Similarity:	143/243 - (58%)	Gaps:	28/243 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 DPKSVLFRLPFARLALVALSLPLGGFFFCVIWSLTFDFVRSTYTHCDVTNYLPSVSAAIGNYEPQ 74
            ||...||||.|..:...|::.|:.|||||:||||.|.|..:..|.|.|.|||||||:|||...||
Human   146 DPDGTLFRLRFTAMVWWAITFPVFGFFFCIIWSLVFHFEYTVATDCGVPNYLPSVSSAIGGEVPQ 210

  Fly    75 KTVWRLAIFLHLPLRLAVAKIYLEHYREHIRRSRRLLGILACF---------------LNVVEDL 124
            :.|||..|.||...|..||..|..||             |:|.               |||||:|
Human   211 RYVWRFCIGLHSAPRFLVAFAYWNHY-------------LSCTSPCSCYRPLCRLNFGLNVVENL 262

  Fly   125 ALFCLSFWTSADHYETHRNAFVVFIACSECYMLVSYLLNRNIQKTVLLPHEEKSLRYKRNLFLVN 189
            ||..|::.:|::.:..|.|||:||||.|..:||::.:|.|..:|..:...:.||..:|:.||::|
Human   263 ALLVLTYVSSSEDFTIHENAFIVFIASSLGHMLLTCILWRLTKKHTVSQEDRKSYSWKQRLFIIN 327

  Fly   190 VIAFGLAGYCFVRHNSHCEAGVYTFFALFEYIVVLTNMGFHMTSYWDF 237
            .|:|..|...:.|||.:|||||||.||:.||.||||||.||||::|||
Human   328 FISFFSALAVYFRHNMYCEAGVYTIFAILEYTVVLTNMAFHMTAWWDF 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PGAP2	NP_608548.1	Frag1	19..240	CDD:287278	103/234 (44%)
PGAP2	XP_011518292.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	198	1.000	Domainoid score	I3086
eggNOG	1	0.900	-	-		E1_KOG3979
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H121634
Inparanoid	1	1.050	203	1.000	Inparanoid score	I3757
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56108
OrthoDB	1	1.010	-	-		D1166083at2759
OrthoFinder	1	1.000	-	-		FOG0003719
OrthoInspector	1	1.000	-	-		oto88819
orthoMCL	1	0.900	-	-		OOG6_107189
Panther	1	1.100	-	-	LDO	PTHR12892
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R277
SonicParanoid	1	1.000	-	-		X4733
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.870