DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PGAP2 and Pgap2

DIOPT Version :9

Sequence 1:	NP_608548.1	Gene:	PGAP2 / 33258	FlyBaseID:	FBgn0031284	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_001369532.1	Gene:	Pgap2 / 233575	MGIID:	2385286	Length:	266	Species:	Mus musculus

Alignment Length:	240	Identity:	110/240 - (45%)
Similarity:	142/240 - (59%)	Gaps:	16/240 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 DPKSVLFRLPFARLALVALSLPLGGFFFCVIWSLTFDFVRSTYTHCDVTNYLPSVSAAIGNYEPQ 74
            |....|.||.|..:||:.:..||..||||::|||.|.|..:|.|||.|.|||||||:|||...||
Mouse    15 DRDGTLVRLRFTMVALITVCCPLVAFFFCILWSLLFHFKETTSTHCGVPNYLPSVSSAIGGEVPQ 79

  Fly    75 KTVWRLAIFLHLPLRLAVAKIYLEHYREHIR--RSRRLLGILACFLNVVEDLALFCLSFWTSADH 137
            :.|||..|.||...|...|..|..||.....  ...|||..:...|||||:|||..|::.:|::.
Mouse    80 RYVWRFCIGLHSAPRFLTAFAYWNHYLSCASPCPGYRLLCRINFSLNVVENLALLVLTYVSSSED 144

  Fly   138 YE----------THRNAFVVFIACSECYMLVSYLLNRNIQKTVLLPHEEKSLRYKRNLFLVNVIA 192
            :.          .|.|||:||||.|..|||::.:|.|..:|..    :.||..:|:.||::|.|:
Mouse   145 FRWCPSSSLPPAIHENAFIVFIAASLGYMLLTCILWRLTKKHT----DRKSYSWKQRLFVINFIS 205

  Fly   193 FGLAGYCFVRHNSHCEAGVYTFFALFEYIVVLTNMGFHMTSYWDF 237
            |..|...:.|||.:|||||||.||:.||.||||||.||||::|||
Mouse   206 FFSALAVYFRHNMYCEAGVYTIFAILEYTVVLTNMAFHMTAWWDF 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PGAP2	NP_608548.1	Frag1	19..240	CDD:287278	106/231 (46%)
Pgap2	NP_001369532.1	Frag1	24..253	CDD:402067	106/231 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	203	1.000	Domainoid score	I2963
eggNOG	1	0.900	-	-		E1_KOG3979
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	208	1.000	Inparanoid score	I3688
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56108
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003719
OrthoInspector	1	1.000	-	-		oto92383
orthoMCL	1	0.900	-	-		OOG6_107189
Panther	1	1.100	-	-	LDO	PTHR12892
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R277
SonicParanoid	1	1.000	-	-		X4733
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.860