DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PGAP2 and pgap-2

DIOPT Version :9

Sequence 1:	NP_608548.1	Gene:	PGAP2 / 33258	FlyBaseID:	FBgn0031284	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_001369853.1	Gene:	pgap-2 / 188041	WormBaseID:	WBGene00007045	Length:	263	Species:	Caenorhabditis elegans

Alignment Length:	244	Identity:	93/244 - (38%)
Similarity:	133/244 - (54%)	Gaps:	12/244 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LFRLPFARLALVALSLPLGGFFFCVIWSLTFDFVRSTYTHCDVTNYLPSVSAAIGNYEPQKTVWR 79
            :..:||....:....||......|||.||...|.::|.|||:|.|:|||:|||:..|.|:|.:||
Worm     8 ILSIPFKYFVICIGGLPSSALLICVILSLLLHFDQATSTHCEVANWLPSISAAVSTYTPEKYIWR 72

  Fly    80 LAIFLHLPLRLAVAKIY--------LEHYREHIRRSRRLLGILACFLNVVEDLALFCLSFWTSAD 136
            :.|.||:..||.||..:        |.....|.|  .|.|..||||||::|:..|..|:..:|::
Worm    73 ILIGLHIGPRLVVAIAFRNFLLGSPLRPLTGHKR--LRFLCNLACFLNLLENFFLLALTSISSSE 135

  Fly   137 HYETHRNAFVVFIACSECYMLVS-YLLNRNIQKTVLLPHEEKSLRYKRNLFLVNVIAFGLAGYCF 200
            .:..|...|..|..||..|||:| :|.|...::|. ....::|..||.....:.|:.|.|..|.:
Worm   136 DHSLHAKCFGGFAICSIIYMLLSTWLFNETGRRTA-TNLGQRSHEYKILGAAIFVLCFFLGAYLY 199

  Fly   201 VRHNSHCEAGVYTFFALFEYIVVLTNMGFHMTSYWDFYALNVVCDAKHG 249
            .|||::||.|:||.|||.||..||:|:.||.|.|:||:..|:|..:..|
Worm   200 WRHNTYCEPGIYTLFALVEYSAVLSNIFFHCTLYYDFHGKNIVLTSSFG 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PGAP2	NP_608548.1	Frag1	19..240	CDD:287278	90/229 (39%)
pgap-2	NP_001369853.1	Frag1	12..239	CDD:402067	90/229 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159530
Domainoid	1	1.000	151	1.000	Domainoid score	I2674
eggNOG	1	0.900	-	-		E1_KOG3979
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H121634
Inparanoid	1	1.050	160	1.000	Inparanoid score	I2876
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56108
OrthoDB	1	1.010	-	-		D1166083at2759
OrthoFinder	1	1.000	-	-		FOG0003719
OrthoInspector	1	1.000	-	-		oto17520
orthoMCL	1	0.900	-	-		OOG6_107189
Panther	1	1.100	-	-	LDO	PTHR12892
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R277
SonicParanoid	1	1.000	-	-		X4733
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	15	14.840