DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PGAP2 and pgap2

DIOPT Version :9

Sequence 1:	NP_608548.1	Gene:	PGAP2 / 33258	FlyBaseID:	FBgn0031284	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	XP_031751495.1	Gene:	pgap2 / 100127662	XenbaseID:	XB-GENE-6454013	Length:	268	Species:	Xenopus tropicalis

Alignment Length:	253	Identity:	101/253 - (39%)
Similarity:	135/253 - (53%)	Gaps:	19/253 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LPTYERFSDPKSVLFRLP---------------FARLALVALSLPLGGFFFCVIWSLTFDFVRST 51
            :||......|..|:|| |               |...|:..:||||..|.||::|||.|:|.|..
Frog     3 IPTDRDRHVPTHVIFR-PTFRGPELGQLALSHSFTTFAVGTVSLPLFAFLFCIVWSLLFNFSRDE 66

  Fly    52 YTHCDVTNYLPSVSAAIGNYEPQKTVWRLAIFLHLPLRLAVAKIYLEHYREHIRRSRRL--LGIL 114
             .|....|||||||||||...||:.:|||.|.||...|..|...||.:|:.....|...  |..|
Frog    67 -LHATGPNYLPSVSAAIGGETPQRYIWRLCIGLHSAPRFLVGVAYLHYYQGTPCSSPAYPRLCHL 130

  Fly   115 ACFLNVVEDLALFCLSFWTSADHYETHRNAFVVFIACSECYMLVSYLLNRNIQKTVLLPHEEKSL 179
            ...||..|...|..|::.:|:::||.|:..|:.|:..|..||.|:..|.|..:|......|..|.
Frog   131 NFLLNCCEIFFLILLTYVSSSENYEVHKLGFMAFMLFSVGYMFVTCSLWRVARKGSGSLEERTSY 195

  Fly   180 RYKRNLFLVNVIAFGLAGYCFVRHNSHCEAGVYTFFALFEYIVVLTNMGFHMTSYWDF 237
            .:|:.||...::.|..:...::.||.:|||||||.|||.||:|||:|||||||::|||
Frog   196 AWKKRLFGFYLLMFLSSILVYIWHNMYCEAGVYTVFALLEYLVVLSNMGFHMTAWWDF 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PGAP2	NP_608548.1	Frag1	19..240	CDD:287278	95/236 (40%)
pgap2	XP_031751495.1	Frag1	34..256	CDD:402067	94/221 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	175	1.000	Domainoid score	I3598
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	179	1.000	Inparanoid score	I3901
OMA	1	1.010	-	-		QHG56108
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003719
OrthoInspector	1	1.000	-	-		otm47760
Panther	1	1.100	-	-	LDO	PTHR12892
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R277
SonicParanoid	1	1.000	-	-		X4733
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	11.100