DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pex12 and PEX12

DIOPT Version :9

Sequence 1:	NP_001259844.1	Gene:	Pex12 / 33256	FlyBaseID:	FBgn0031282	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	NP_001325637.1	Gene:	PEX12 / 819602	AraportID:	AT3G04460	Length:	403	Species:	Arabidopsis thaliana

Alignment Length:	332	Identity:	69/332 - (20%)
Similarity:	108/332 - (32%)	Gaps:	125/332 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 PSIFEISASETLDNLIYPALSKIFDYFGLRLDFKLWGSLRIQEELSPLLTWLLQYLYLRKRASSF 79
            |:.||::|::.|...:..||:.....|.||..| |...|..::|....|..:|:...||....||
plant    12 PTFFEMAAAQQLPASLRAALTYSLGVFALRRSF-LHKILDYEDEFFAALMLILEGHSLRTTDGSF 75

  Fly    80 GESFYGLQR------------------TVTTTGDLLNRRQQFASATLLTFMPYV----------E 116
            .||.|||:|                  .|..:|  |.:||:..|...|..:||.          |
plant    76 AESLYGLRRKSARLRLRKDSARKDSSEEVQHSG--LEKRQRILSVVFLVVLPYFKSKLHAIYNKE 138

  Fly   117 RKLRTR-----------------------ITR----HEDTS-----------------PWEQRLL 137
            |:.|.|                       ::|    :|:.|                 ||
plant   139 REARLRESLWGAEDQGFDEADFFTGDDSIVSREPSGNEELSVRVQLATKIKKFIAVCYPW----- 198

  Fly   138 SAFHAFHAAKAAHTFFYLVKYASNHSPIFRL----LGLTL-------------------RYPSEP 179
                 .||:....:|.|.:.|..:.:..:.|    ||:.:                   .:..|.
plant   199 -----IHASSEGLSFTYQLLYLLDATGFYSLGLQALGIQVCRATGQELMDTSSRISKIRNHERER 258

  Fly   180 PKEDQW-----------TYVVLKM----LEVLAFFLQFVQWWYSNDQRRKVGGTLINPEAMPRKQ 229
            .:...|           :|.||..    |....|..:.::|||.:.:.|....|:..|.  |...
plant   259 LRGPPWLKTVQGALLSCSYAVLDYAQTGLIAAVFIFKMMEWWYQSAEERLSAPTVYPPP--PPPP 321

  Fly   230 LPKEVQQ 236
            .||.:.|
plant   322 APKVINQ 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pex12	NP_001259844.1	Pex2_Pex12	24..209	CDD:282595	58/294 (20%)
Pex12	NP_001259844.1	zf-RING_2	242..281	CDD:290367
PEX12	NP_001325637.1	Pex2_Pex12	20..303	CDD:398431	58/295 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	59	1.000	Domainoid score	I3916
eggNOG	1	0.900	-	-		E1_KOG0826
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H240
Inparanoid	1	1.050	114	1.000	Inparanoid score	I2037
OMA	1	1.010	-	-		QHG55389
OrthoDB	1	1.010	-	-		D1204472at2759
OrthoFinder	1	1.000	-	-		FOG0005079
OrthoInspector	1	1.000	-	-		oto3966
orthoMCL	1	0.900	-	-		OOG6_103569
Panther	1	1.100	-	-	LDO	PTHR12888
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5424
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840