Protein Alignment Saf6 and Saf6

DIOPT Version :10

• Sequence 1: NP_608545.1
• Gene: Saf6 / 33255
• FlyBaseID: FBgn0031281
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: XP_061517310.1
• Gene: Saf6 / 1277719
• VectorBaseID: AGAMI1_004171
• Length: 886
• Species: Anopheles gambiae
• Alignment Length: 917
• Identity: 238/917 - (25%)
• Similarity: 366/917 - (39%)
• Gaps: 285/917 - (31%)

  Fly    14 KSSHSKVSKKSTKSRSKSAKLELTGKNSLSASAS---SSIASAVSGG---VAVGSLPATPTHLNM 72
            |.|.||| |:.|||.|..........|:.|...|   ::..:||||.   .|..|..:...||:.
Mosquito    12 KKSSSKV-KQRTKSSSSGTNANNNNNNNSSTPTSNQQNAAGTAVSGAGQTSAANSNQSQQQHLHP 75

  Fly    73 VTTPTTPTSSLGNYNLFDASFAVAGSGGHGLAGGIAGAEASGNS-SRMG------HQKSYAGFDP 130
            ......|.|                             ::|||. |.||      ..|||||...
Mosquito    76 PPKQAVPHS-----------------------------DSSGNDVSNMGSAKDKTSYKSYAGLSS 111

  Fly   131 RSIKIFWEQHDQTDVELSQDVCARLAEDASYKVWELINNVKIYSRHSGGVVTYDLVNEVLKDADV 195
            ||::..|||||:.:.|::.||..:|||||:||:|||.|::|.|||||.|.||:|||||||||:||
Mosquito   112 RSVRTAWEQHDKQETEVAPDVYTKLAEDATYKLWELTNSIKTYSRHSSGRVTFDLVNEVLKDSDV 176

  Fly   196 PPMLGAMDSDWDRIDYDGSFYFHSDKIFELSAEFQKEVNLCTPDDADFQSICPVEDKHMDQLRQC 260
            ||::||....||:|:|||:::|:||::.:|..|:.|.::|...:.....:....|....:.|...
Mosquito   177 PPIVGANSQPWDKIEYDGAYFFNSDEVLDLREEYIKHISLEQHNVPVLTTTWMAEADIAEDLIAM 241

  Fly   261 VQSLVTAALFADSKSQTAAV---CHAFQTPLMGSIYRVIVSKMVQLLAFKQQDHLSQRCWRLLRA 322
            ..::..|....|..|...|:   .:...||   |:.:::::|.:::|.|:..:...:|....|.|
Mosquito   242 HNNICDAIFIGDEASFNTAIDILQYNRHTP---SLMKLLLTKAIEMLGFEYTEATLRRTLVYLEA 303

  Fly   323 CNYNATANHNACRPEYFNLAEVLVSQLMAPYETIKAPHVDP--------------DPGQTTSIKM 373
            ...|....|:....|...|:::.|:.|:.|...:.|..:.|              ||.|....:.
Mosquito   304 LVQNYHVAHSDLTLELSLLSQLFVNLLVGPAGYVHAKLMQPNDPVPRPVTSLVGNDPQQQPQQQQ 368

  Fly   374 EFEEEL-KVEP----------------DQCHNPETQENPEVM----------------------- 398
            :.::.| .:.|                :..:|..:....|::
Mosquito   369 QQQQVLDNISPLFNNPMALLENNLPPAEDSNNSNSNATEELLRSIENIKDGADGIDLNNKDDYEA 433

  Fly   399 ----------GVE-------------------KQEQEPQMF------------------PGEST- 415
                      ||:                   |.|.:|:.|                  ||..|
Mosquito   434 LFSMVLGKQEGVDEGMVGTESMADGVVDGFQVKSEFDPEAFEANASNFIVQQASGSVVGPGGHTA 498

  Fly   416 ---------------------------------------MEH----------------TIYKLQS 425
                                                   |.|                ||.....
Mosquito   499 HPGTMADPGMLTNEMLNSLAASAAAAAAATGASVNSDMGMFHIKPDPGKPKLDSGTPPTIIDADP 563

  Fly   426 EE--------------EELNPQP---EAEHLSSYFACPVGNGLVDELCETIGQLASQSGYLHAEC 473
            ||              |..||..   |:|:::: ..|.  :.|||.:|..:|..||:.|::..||
Mosquito   564 EENVSLPMSESSDGGGEVNNPNSTTLESENITT-LICE--DYLVDGVCRVVGLCASKWGFVEQEC 625

  Fly   474 LFLIKRRLARFFEGRHVSSERDFRYISRAVRGLIALGEYAFREFIPYIYKLRVEEIPDSLWPDLA 538
            .||:..||.|:|:.|..::. |:.::||..|||.|:||:|.||.:||.|.:..:.||:.|.|...
Mosquito   626 TFLLVERLQRYFQERKTATV-DYNWLSRIFRGLWAIGEFALRELLPYFYYIDSQTIPECLVPHFN 689

  Fly   539 PAAIFLGGHDDVYLYEWLEYGCGAALQPFLVHYARAYEKMVTRRYVK-----AKQPAYRIESVPG 598
            .|.||:.|..|::.||:|...||.:|.||:..|.:..||...:.:.|     |.:..|::.:...
Mosquito   690 TAGIFMNGRSDIFFYEYLYDICGDSLGPFMFSYDQYIEKQCLKYHRKRLKIIANKSCYKVAAKVV 754

  Fly   599 VRRLEWSTLAAAMCHGDDPS---KALKPKPTLCEAF--------PDLQSPNLQLNCAGNIRFKFA 652
            .:||              |:   :|.|.||||.|||        |.|.|||....  ....|:||
Mosquito   755 PKRL--------------PAYIPRAAKAKPTLQEAFENYSEKRLPPLSSPNQAPK--AQFGFRFA 803

  Fly   653 GCRPVLLKPKVATVPHSEDSPSSAANGGGGGGA----------------------SSDILIAKRK 695
            ||||:.||    |....:.|.|:||:......:                      :|.|::|:|:
Mosquito   804 GCRPIPLK----TAQSRQKSASAAASASITNSSMPLGTETVEGMLKQNTPLLSSFNSKIVVARRR 864

  Fly   696 LFKPLTN 702
            |..|.||
Mosquito   865 LLSPATN 871

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Saf6	NP_608545.1	HFD_TAF6L	128..200	CDD:467056	43/71 (61%)
Saf6	XP_061517310.1	None