Protein Alignment Dbp21E2 and MRH4

DIOPT Version :10

• Sequence 1: NP_608544.1
• Gene: Dbp21E2 / 33254
• FlyBaseID: FBgn0086130
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_011451.1
• Gene: MRH4 / 852816
• SGDID: S000003032
• Length: 561
• Species: Saccharomyces cerevisiae
• Alignment Length: 555
• Identity: 142/555 - (25%)
• Similarity: 235/555 - (42%)
• Gaps: 142/555 - (25%)

  Fly     6 VVLRVQSSRHVASYA---------TAAAAAVKT----KPPKAKSKGKK--QKGEPLISCRRSQFD 55
            |:|::    .|.|||         .:..|:|.|    |..|.|:||||  :|.:|     ...|:
Yeast    17 VLLKI----GVRSYAGGPRTKHKGNSPLASVPTGSSNKNRKQKAKGKKGNKKNDP-----DQAFN 72

  Fly    56 LTQYE--QTDAKFGSLSLASKGWLHNK-SKGDFFILNASVRG---EELQQEMQTVDEFLESTGMQ 114
            ..:|.  :.|.:   :::.|...|..| |..|..::...||.   |.:.:|...:.:..:.|...
Yeast    73 FGEYGGLKKDVE---MNMDSTNKLIQKISNFDQLLILPPVRDAVKEIISKESLKLQDSRKKTSEN 134

  Fly   115 IHPQLLENLRVELGIKLLTGIQKQGMPVVHGNEHCLIAAETGCGKTITYLLPIVDKLLQKEVVTE 179
            |.|..::.:.::...|.|...:.|    :|.     ||||||.|||:.||:|::|.|.::|:.|.
Yeast   135 IIPSPIQTVAIKRISKNLMDPKLQ----IHA-----IAAETGSGKTMAYLIPLIDYLKRQELETP 190

  Fly   180 ------RKLNTPRVLILTPGRELATQIAGVTEKLTQGTNLKVQSLLGGNT---------KQLMMN 229
                  ||....|.:||.|..||..|:        ..|..|.::|||.|:         :.|:.|
Yeast   191 ELWETLRKNVLIRSIILVPTHELVDQV--------YETVSKTKTLLGLNSFKWDKATSYRDLLEN 247

  Fly   230 PQFEEVDILVATLGAL-----SKLVTTGIYRMEQVRHLVLDEADTLLDDTFTDKLSYFLRRFP-- 287
            .: ..:||||.|.|.|     .:::|.....:.:|..:||||||||||.::.::....::|.|
Yeast   248 IK-NRIDILVTTPGKLLNLFSIRMITRPDKVLSKVGFVVLDEADTLLDRSWLEETHSAIKRIPNI 311

  Fly   288 FHLVQKEDAGTQMILASATMPTNTREILHKVIDVDTIREVVSPHLHRLMSHVTQKFL-------R 345
            .||          |..|||:|....:.:.::.  .|:..:::|.||:|...:..|.:       :
Yeast   312 NHL----------IFCSATIPQEFNKTMQRLF--PTVVPIMTPRLHKLPFALDFKVINSALSPFK 364

  Fly   346 LSKADRPATLLSLVKHDLA----KRRPLIVFSNKSTTSDFVSIFLNNSGVNCLNLNGDMLMKIR- 405
            .||....|..|..:.:|..    ::|.:|..:.|....:.|::.....|.|.:.|.|:...:.|
Yeast   365 GSKIKALAQTLYAISNDDTEPGFEKRCIIFVNEKKNVPEIVNLLNKKFGHNAIGLTGEDTFEERS 429

  Fly   406 --------------------------LGRFE---------QFQNGHCD----------VLSTTDV 425
                                      |.:||         :.:|.:.:          ||.|||:
Yeast   430 EKIMPFLSPPRPLSEVVAQSTSPPTSLKKFEIPDSNIVIGKLKNTNSNGTAPSNKSLHVLVTTDL 494

  Fly   426 GSRGLDTTRARHVVNFDFPLHVSDYIHRCGRIGRV 460
            .:|||:....|:||.:|.|....|.|||.||..|:
Yeast   495 MARGLNFKGVRNVVLYDVPKTSIDLIHRVGRTARM 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dbp21E2	NP_608544.1	DEADc_DDX28	119..345	CDD:350706	71/254 (28%)
		SF2_C_DEAD	339..462	CDD:350174	39/179 (22%)
MRH4	NP_011451.1	DEADc_MRH4	100..346	CDD:350723	76/275 (28%)
		SF2_C_DEAD	384..538	CDD:350174	33/146 (23%)