DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dbp21E2 and CG32344

DIOPT Version :9

Sequence 1:	NP_608544.1	Gene:	Dbp21E2 / 33254	FlyBaseID:	FBgn0086130	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	NP_612028.4	Gene:	CG32344 / 326208	FlyBaseID:	FBgn0052344	Length:	827	Species:	Drosophila melanogaster

Alignment Length:	357	Identity:	103/357 - (28%)
Similarity:	165/357 - (46%)	Gaps:	38/357 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 LGIKLLTGIQKQG-----------MPVVHGNEHCLIAAETGCGKTITYLLPIVDKLLQKEVVTER 180
            ||.:|:.||.|:|           :|::......:..|:||.|||..:|:|:.:||.::|
  Fly    46 LGFELIKGITKRGYKVPTPIQRKTIPLILEGRDVVAMAKTGSGKTACFLIPLFEKLQRRE----- 105

  Fly   181 KLNTPRVLILTPGRELATQIAGVTEKLTQGTNLKVQSLLGGNTKQLMMNPQFEEV----DILVAT 241
            .....|.|||:|.||||.|.....::|.:...||...:|||::    |:.||..:    |::|||
  Fly   106 PTKGARALILSPTRELAVQTYKFIKELGRFMELKSILVLGGDS----MDSQFSAIHTCPDVIVAT 166

  Fly   242 LGALSKLVTTGIYRMEQVRHLVLDEADTLLDDTFTDKLSYFLRRFPFHLVQKEDAGTQMILASAT 306
            .|....|......::..:.::|.||||.|.:..|.::|:..|.|.|        :..|.::.|||
  Fly   167 PGRFLHLCVEMDLKLNSIEYVVFDEADRLFEMGFGEQLNETLHRLP--------SSRQTVMFSAT 223

  Fly   307 MPTNTREILHKVI-DVDTIR-EVVSPHLHRLMSHVTQKFLRLSKADRPATLLSLVKHDLAKRRPL 369
            :|....|.....: |...|| :|.|    :|...:..|||.....||...|:.|:|:.:..:...
  Fly   224 LPKLLVEFARAGLNDPVLIRLDVES----KLPDALALKFLYCRPDDRYTALVVLLKYVIPVQSQT 284

  Fly   370 IVFSNKSTTSDFVSIFLNNSGVNCLNLNGDMLMKIRLGRFEQFQNGHCDVLSTTDVGSRGLDTTR 434
            :||:......:.:|..|..:|::..::...:....|.....:|.|....||..|||.:||:|...
  Fly   285 VVFAGTQHHVELISYILTEAGISNASVYSSLDPAARKINTAKFVNKKVSVLIVTDVAARGIDIPS 349

  Fly   435 ARHVVNFDFPLHVSDYIHRCGRIGRVGNMDKA 466
            ...|||..||.....::||.||..|.|....|
  Fly   350 LDFVVNLHFPGKPKLFVHRVGRCARAGRTGTA 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dbp21E2	NP_608544.1	P-loop_NTPase	113..314	CDD:304359	60/201 (30%)
		DEXDc	126..330	CDD:214692	65/219 (30%)
		HELICc	343..462	CDD:238034	33/118 (28%)
CG32344	NP_612028.4	DEADc	41..243	CDD:238167	62/213 (29%)
		DEXDc	54..243	CDD:214692	58/205 (28%)
		HELICc	263..384	CDD:238034	33/119 (28%)
		DBP10CT	666..721	CDD:285373
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451633
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24031
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030