Protein Alignment Dbp21E2 and Prp5

DIOPT Version :10

• Sequence 1: NP_608544.1
• Gene: Dbp21E2 / 33254
• FlyBaseID: FBgn0086130
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_573020.2
• Gene: Prp5 / 32464
• FlyBaseID: FBgn0030631
• Length: 1224
• Species: Drosophila melanogaster
• Alignment Length: 562
• Identity: 145/562 - (25%)
• Similarity: 237/562 - (42%)
• Gaps: 116/562 - (20%)

  Fly    32 PKAKSKG---------KK----QKGEPLISCRRSQFDLTQY----EQTDAKFGSLSLASKGWLHN 79
            |.|||:|         ||    :|||.:    ....|..:|    |..|.:..:::||.|   |.
  Fly   396 PPAKSQGVVILTGVAKKKTTTLKKGEVI----EQNMDSLEYSSEDELEDIRDTAVNLAMK---HR 453

  Fly    80 K--SKGDF-------FILNASVRGEELQQ----EMQTVDEFLESTGMQ----------------- 114
            |  :|.|.       |..|..|...||.:    :::.....||  |:|
  Fly   454 KELAKIDHSSVTYAPFRKNFYVEVPELTRMTAADVEKYRSDLE--GIQVKGKGCPKPIKTWAQCG 516

  Fly   115 IHPQLLENLRVELGIKLLTGIQKQGMPVVHGNEHCLIAAETGCGKTITYLLPIVDKLLQKEVVTE 179
            :..:.:|.|| .||.:..|.||.|.:|.:......:..|:||.|||:.::||:...:|.:..:.:
  Fly   517 VSKKEMEVLR-RLGFEKPTPIQCQAIPAIMSGRDLIGIAKTGSGKTLAFILPMFRHILDQPSMED 580

  Fly   180 RKLNTPRVLILTPGRELATQIAGVTEKLTQGTNLKVQSLLGGNTKQLMMNPQFEEV----DILVA 240
            .  :....:|:.|.|||..||.....|.::...|:...:.||..    ::.|..|:    :|:|.
  Fly   581 G--DGAIAIIMAPTRELCMQIGKDIRKFSKSLGLRPVCVYGGTG----ISEQIAELKRGAEIIVC 639

  Fly   241 TLGALSKLVTTG---IYRMEQVRHLVLDEADTLLDDTFTDKLSYFLRRFPFHLVQKEDAGTQMIL 302
            |.|.:..::...   :..:.:|.::||||||.:.|..|..::        ..::.......|.::
  Fly   640 TPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQV--------MRIIDNVRPDRQTVM 696

  Fly   303 ASATMPTN----TREILHKVIDVDT-IREVVSPHL--HRLMSHVTQKFLRLSKADRPATLLSLVK 360
            .|||.|..    .|.||.|.|:|.. .|.||...:  |.::.:...||.:|.:      ||.:.:
  Fly   697 FSATFPRQMEALARRILKKPIEVIVGGRSVVCKEVEQHVVILNDDAKFFKLLE------LLGIYQ 755

  Fly   361 HDLAKRRPLIVFSNKSTTSDFVSIFLNNSGVNCLNLNGDMLMKIRLGRFEQFQNGHCDVLSTTDV 425
                :...:|||.:|...:|.:...|..:...|::|:|.:....|......|::|...:|..|.|
  Fly   756 ----EAGSIIVFVDKQENADILLRDLMKASYPCMSLHGGIDQFDRDSTIIDFKSGKVRLLIATSV 816

  Fly   426 GSRGLDTTRARHVVNFDFPLHVSDYIHRCGRIGRVGNMDKA--LVTNLISSRREIDVVQRIEHAA 488
            .:||||......|||:|.|.|..||:|||||.||.|....|  .:|. ..||...|:::.::
  Fly   817 AARGLDVKDLILVVNYDVPNHYEDYVHRCGRTGRAGKKGSAYTFITP-EQSRYAGDIIRAMD--- 877

  Fly   489 RTGGLLPDVNANIRNIINKRIVAEMKAAGMPVPALGSLNGHT 530
            .:|.|:|               ||::|......||....|.|
  Fly   878 LSGTLIP---------------AELQALWTEYKALQEAEGKT 904

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dbp21E2	NP_608544.1	DEADc_DDX28	119..345	CDD:350706	62/239 (26%)
		SF2_C_DEAD	339..462	CDD:350174	39/122 (32%)
Prp5	NP_573020.2	Trypan_PARP	<291..383	CDD:368653
		DEAD-like_helicase_N	454..899	CDD:475120	125/490 (26%)
		KH-I_DDX46	1121..1223	CDD:411901