Protein Alignment Pkg21D and TPK2

DIOPT Version :10

• Sequence 1: NP_477213.1
• Gene: Pkg21D / 33253
• FlyBaseID: FBgn0000442
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: NP_015121.1
• Gene: TPK2 / 855898
• SGDID: S000006124
• Length: 380
• Species: Saccharomyces cerevisiae
• Alignment Length: 333
• Identity: 130/333 - (39%)
• Similarity: 199/333 - (59%)
• Gaps: 16/333 - (4%)

  Fly   428 LAMKQAQESCRDEPKEQLQQEFPDLKLT--------DLEVVSTLGIGGFGRVELVKAHHQDRVDI 484
            |..:|.|:..| :.::.|..:.|...|.        |.:::.|||.|.||||.||::.|..|  .
Yeast    34 LQQRQQQQQQR-QHQQLLTSQLPQKSLVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGR--Y 95

  Fly   485 FALKCLKKRHIVDTKQEEHIFSERHIMLSSRSPFICRLYRTFRDEKYVYMLLEACMGGEIWTMLR 549
            :|:|.|||:.:|..||.||...||.::.....||:.|::.||:|.:.::|:::...|||::::||
Yeast    96 YAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLR 160

  Fly   550 DRGSFEDNAAQFIIGCVLQAFEYLHARGIIYRDLKPENLMLDERGYVKIVDFGFAKQIGTSSKTW 614
            ....|.:..|:|....|:.|.|||||..||||||||||::||..|::||.||||||::.|  .||
Yeast   161 KSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQT--VTW 223

  Fly   615 TFCGTPEYVAPEIILNKGHDRAVDYWALGILIHELLNGTPPFSAPDPMQTYNLILKGIDMIAFPK 679
            |.||||:|:|||:|..|.::::||:|:||:||:|:|.|..||....||:||..||:|  .:.:|.
Yeast   224 TLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQG--KVVYPP 286

  Fly   680 HISRWAVQLIKRLCRDVPSERLGYQTGGIQDIKKHKWFLGFDWDGLASQLLIPPFVRPIAHPT-D 743
            :.....|.|:.:|.....:.|:|....|.:|||.|.||....|:.|.::.:..|:..||.... |
Yeast   287 YFHPDVVDLLSKLITADLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEPPITSGIGD 351

  Fly   744 VRYFDRFP 751
            ...||::|
Yeast   352 TSLFDQYP 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkg21D	NP_477213.1	CAP_ED	185..285	CDD:237999
		CAP_ED	304..419	CDD:237999
		STKc_cGK	463..724	CDD:270724	113/260 (43%)
		S_TK_X	719..>760	CDD:214529	9/34 (26%)
TPK2	NP_015121.1	STKc_PKA_like	69..358	CDD:270732	122/294 (41%)