Protein Alignment Pkg21D and YPK1

DIOPT Version :10

• Sequence 1: NP_477213.1
• Gene: Pkg21D / 33253
• FlyBaseID: FBgn0000442
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: NP_012796.1
• Gene: YPK1 / 853733
• SGDID: S000001609
• Length: 680
• Species: Saccharomyces cerevisiae
• Alignment Length: 326
• Identity: 111/326 - (34%)
• Similarity: 178/326 - (54%)
• Gaps: 19/326 - (5%)

  Fly   452 LKLTDLEVVSTLGIGGFGRVELVKAHHQDRVDIFALKCLKKRHIVDTKQEEHIFSERHIMLSSRS 516
            |.:.|.:::..:|.|.||:|  ::...:|...::|||.::|.:||...:..|..:||.::.....
Yeast   342 LSIDDFDLLKVIGKGSFGKV--MQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARVDC 404

  Fly   517 PFICRLYRTFRDEKYVYMLLEACMGGEIWTMLRDRGSFEDNAAQFIIGCVLQAFEYLHARGIIYR 581
            |||..|..:|:..:.:|.:|....|||::..|:..|.|:.:.|:|....:|.|.:.||...::||
Yeast   405 PFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYR 469

  Fly   582 DLKPENLMLDERGYVKIVDFGFAK-QIGTSSKTWTFCGTPEYVAPEIILNKGHDRAVDYWALGIL 645
            ||||||::||.:|::.:.|||..| .:....||.||||||||:|||::|..|:.:|||:|.||:|
Yeast   470 DLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVL 534

  Fly   646 IHELLNGTPPFSAPDPMQTYNLILKGIDMIAFPKHISRWAVQLIKRLCRDVPSERLGYQTGGIQD 710
            ::|:|.|.||:...|..:.|..||:  :.:.||....|.|..|:..|....|:.||||  .|..:
Yeast   535 LYEMLTGLPPYYDEDVPKMYKKILQ--EPLVFPDGFDRDAKDLLIGLLSRDPTRRLGY--NGADE 595

  Fly   711 IKKHKWFLGFDWDGLASQLLIPPFVRPIAHPTDVRYFD-----RFPCD------LNEP-PDELSG 763
            |:.|.:|....|..|..:..|||:...:::..|...||     ..|.|      |:|. ..:..|
Yeast   596 IRNHPFFSQLSWKRLLMKGYIPPYKPAVSNSMDTSNFDEEFTREKPIDSVVDEYLSESVQKQFGG 660

  Fly   764 W 764
            |
Yeast   661 W 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkg21D	NP_477213.1	CAP_ED	185..285	CDD:237999
		CAP_ED	304..419	CDD:237999
		STKc_cGK	463..724	CDD:270724	96/261 (37%)
		S_TK_X	719..>760	CDD:214529	12/52 (23%)
YPK1	NP_012796.1	YPK1_N_like	116..342	CDD:212165	111/326 (34%)
		Protein Kinases, catalytic domain	352..663	CDD:473864	109/316 (34%)