Protein Alignment Pkg21D and TPK3

DIOPT Version :10

• Sequence 1: NP_477213.1
• Gene: Pkg21D / 33253
• FlyBaseID: FBgn0000442
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: NP_012755.1
• Gene: TPK3 / 853688
• SGDID: S000001649
• Length: 398
• Species: Saccharomyces cerevisiae
• Alignment Length: 333
• Identity: 134/333 - (40%)
• Similarity: 199/333 - (59%)
• Gaps: 10/333 - (3%)

  Fly   422 GDESRKLAMKQAQESCR-DEPKEQLQQEFPDLKLTDLEVVSTLGIGGFGRVELVKAHHQDRVDIF 485
            |..|.||..:.:...|. .:|..|.:.......|:|.:::.|||.|.||||.|::::|..|  .:
Yeast    52 GRNSGKLKEEASAGICLVKKPMLQYRDTSGKYSLSDFQILRTLGTGSFGRVHLIRSNHNGR--FY 114

  Fly   486 ALKCLKKRHIVDTKQEEHIFSERHIMLSSRSPFICRLYRTFRDEKYVYMLLEACMGGEIWTMLRD 550
            |||.|||..||..||.||...||.::.....|||.|::.||:|.:.|:|:::...|||::::||.
Yeast   115 ALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRK 179

  Fly   551 RGSFEDNAAQFIIGCVLQAFEYLHARGIIYRDLKPENLMLDERGYVKIVDFGFAKQIGTSSKTWT 615
            ...|.:..|:|....|..|.||||::.||||||||||::||:.|::||.||||||.:  ...|:|
Yeast   180 SQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYV--PDVTYT 242

  Fly   616 FCGTPEYVAPEIILNKGHDRAVDYWALGILIHELLNGTPPFSAPDPMQTYNLILKGIDMIAFPKH 680
            .||||:|:|||::..|.::::||:|:.|:||:|:|.|..||...:.|:||..||..  .:.||..
Yeast   243 LCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNA--ELKFPPF 305

  Fly   681 ISRWAVQLIKRL-CRDVPSERLGYQTGGIQDIKKHKWFLGFDWDGLASQLLIPPFVRPIAH-PTD 743
            ....|..|:|:| .||: |||||....|.:|:|.|.||....|:.|.::.:..|:..||.. ..|
Yeast   306 FHPDAQDLLKKLITRDL-SERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGD 369

  Fly   744 VRYFDRFP 751
            ...|||:|
Yeast   370 TSQFDRYP 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkg21D	NP_477213.1	CAP_ED	185..285	CDD:237999
		CAP_ED	304..419	CDD:237999
		STKc_cGK	463..724	CDD:270724	115/261 (44%)
		S_TK_X	719..>760	CDD:214529	10/34 (29%)
TPK3	NP_012755.1	STKc_PKA_like	86..376	CDD:270732	124/296 (42%)