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Protein Alignment Pkg21D and RPS6KB2

DIOPT Version :10

Sequence 1:	NP_477213.1	Gene:	Pkg21D / 33253	FlyBaseID:	FBgn0000442	Length:	768	Species:	Drosophila melanogaster
Sequence 2:	NP_003943.2	Gene:	RPS6KB2 / 6199	HGNCID:	10437	Length:	482	Species:	Homo sapiens

Alignment Length:	372	Identity:	129/372 - (34%)
Similarity:	209/372 - (56%)	Gaps:	37/372 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   418 EKDYGDESRKLAMKQAQESCRDEPKEQLQQ-------EFPDLKLTD--------------LEVVS 461
            |.:.|.|..........::|   |..:|:.       .:.:::||:              .|::.
Human    10 ETEEGSEGEGEPELSPADAC---PLAELRAAGLEPVGHYEEVELTETSVNVGPERIGPHCFELLR 71

  Fly   462 TLGIGGFGRV-ELVKAHHQDRVDIFALKCLKKRHIV-DTKQEEHIFSERHIMLSSRSPFICRLYR 524
            .||.||:|:| ::.|....:...|:|:|.|:|..|| :.|...|..:||:|:.|.:.|||..|..
Human    72 VLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHPFIVELAY 136

  Fly   525 TFRDEKYVYMLLEACMGGEIWTMLRDRGSFEDNAAQFIIGCVLQAFEYLHARGIIYRDLKPENLM 589
            .|:....:|::||...|||::|.|...|.|.::.|.|.:..:..|..:||::|||||||||||:|
Human   137 AFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIM 201

  Fly   590 LDERGYVKIVDFGFAKQ-IGTSSKTWTFCGTPEYVAPEIILNKGHDRAVDYWALGILIHELLNGT 653
            |..:|::|:.|||..|: |...:.|.|||||.||:||||::..||:||||:|:||.|::::|.|:
Human   202 LSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGS 266

  Fly   654 PPFSAPDPMQTYNLILKGIDMIAFPKHISRWAVQLIKRLCRDVPSERLGYQTGGIQDIKKHKWFL 718
            |||:|.:..:|.:.|::|  .:|.|.:::..|..|:|:..:..||:|:|...|...|:::|.:|.
Human   267 PPFTAENRKKTMDKIIRG--KLALPPYLTPDARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFFR 329

  Fly   719 GFDWDGLASQLLIPPFVRPIAHPTDVRYFD-RF----PCDLNEPPDE 760
            ..:||.|.:..:.|||...:....||..|| ||    |.|   .||:
Human   330 HMNWDDLLAWRVDPPFRPCLQSEEDVSQFDTRFTRQTPVD---SPDD 373

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.