DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pkg21D and akt3a

DIOPT Version :10

Sequence 1:NP_477213.1 Gene:Pkg21D / 33253 FlyBaseID:FBgn0000442 Length:768 Species:Drosophila melanogaster
Sequence 2:NP_001184130.1 Gene:akt3a / 560549 ZFINID:ZDB-GENE-050419-180 Length:479 Species:Danio rerio


Alignment Length:348 Identity:117/348 - (33%)
Similarity:194/348 - (55%) Gaps:20/348 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly   417 KEKDYGDESRKLA----MKQAQESCRDEPKEQLQ---QEFPDLKLT--------DLEVVSTLGIG 466
            :|:|...|:.::.    .:|.:|..:..|..|:.   :|..|..::        |.:.:..||.|
Zfish    93 EERDEWAEAIQMVADKLQRQEEERIQCSPTSQIDNMGEEEMDTSISHHKRKTMNDFDYLKLLGKG 157

  Fly   467 GFGRVELVKAHHQDRVDIFALKCLKKRHIVDTKQEEHIFSERHIMLSSRSPFICRLYRTFRDEKY 531
            .||:|.||:.....:  .:|:|.|||..|:...:..|..:|..::.::|.||:..|..:|:.:..
Zfish   158 TFGKVILVREKASGK--YYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDR 220

  Fly   532 VYMLLEACMGGEIWTMLRDRGSFEDNAAQFIIGCVLQAFEYLHARGIIYRDLKPENLMLDERGYV 596
            :..::|...|||::..|.....|.::..:|....::.|.:|||:..|:|||||.||||||:.|::
Zfish   221 LCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSAKIVYRDLKLENLMLDKDGHI 285

  Fly   597 KIVDFGFAKQIGTSSKTW-TFCGTPEYVAPEIILNKGHDRAVDYWALGILIHELLNGTPPFSAPD 660
            ||.|||..|:..|.:.|. ||||||||:|||::.:..:.||||:|.||::::|::.|..||...|
Zfish   286 KITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQD 350

  Fly   661 PMQTYNLILKGIDMIAFPKHISRWAVQLIKRLCRDVPSERLGYQTGGIQDIKKHKWFLGFDWDGL 725
            ..:.:.|||  ::.|.||:.:|..|..|:..|....|::|||......::|.:|.:|.|.||..:
Zfish   351 HEKLFELIL--MEDIKFPRTLSADAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFTGIDWQDV 413

  Fly   726 ASQLLIPPFVRPIAHPTDVRYFD 748
            ..:.|||||...::..||.||||
Zfish   414 YDKKLIPPFKPQVSSETDTRYFD 436

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Pkg21DNP_477213.1 CAP_ED 185..285 CDD:237999
CAP_ED 304..419 CDD:237999 0/1 (0%)
STKc_cGK 463..724 CDD:270724 96/261 (37%)
S_TK_X 719..>760 CDD:214529 14/30 (47%)
akt3aNP_001184130.1 PH_PKB 4..110 CDD:269947 3/16 (19%)
STKc_PKB_gamma 132..479 CDD:270745 109/309 (35%)
Blue background indicates that the domain is not in the aligned region.

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