DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pkg21D and CG12069

DIOPT Version :9

Sequence 1:	NP_477213.1	Gene:	Pkg21D / 33253	FlyBaseID:	FBgn0000442	Length:	768	Species:	Drosophila melanogaster
Sequence 2:	NP_651819.1	Gene:	CG12069 / 43643	FlyBaseID:	FBgn0039796	Length:	356	Species:	Drosophila melanogaster

Alignment Length:	319	Identity:	122/319 - (38%)
Similarity:	183/319 - (57%)	Gaps:	14/319 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   439 DEPKEQLQQEF------PDLKLTDLEVVSTLGIGGFGRVELVKAHHQDRVDIFALKCLKKRHIVD 497
            |:.:|...::|      |...|.|.|:.:|||.|.||:|:||:  .::....:|.|.|.|..||.
  Fly    23 DKLREDFNKKFATNTPSPSTGLDDYEIKATLGSGSFGKVQLVR--ERESGVYYASKQLSKDQIVK 85

  Fly   498 TKQEEHIFSERHIMLSSRSPFICRLYRTFRDEKYVYMLLEACMGGEIWTMLRDRGSFEDNAAQFI 562
            |||..|:.||::::.|...|....|..:::|...:|::|....|||::|..|....|.:..|:|.
  Fly    86 TKQVSHVMSEKNVLRSMTFPNTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRKFTEKQARFY 150

  Fly   563 IGCVLQAFEYLHARGIIYRDLKPENLMLDERGYVKIVDFGFAKQIGTSSKTWTFCGTPEYVAPEI 627
            ...|..|.||||...::||||||||:|:|:.||:|:.||||||::.|  :|.|.||||||:.|||
  Fly   151 AAQVFLALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAKKVET--RTMTLCGTPEYLPPEI 213

  Fly   628 ILNKGHDRAVDYWALGILIHELLNGTPPFSA--PDPMQTYNLILKGIDMIAFPKHISRWAVQLIK 690
            |.:|.:..:||:||.|:|:.|.:.|..||||  .|.|..||.|.:.  ....|.:.|.....|:.
  Fly   214 IQSKPYGTSVDWWAFGVLVFEFVAGHSPFSAHNRDVMSMYNKICEA--DYKMPSYFSGALRHLVD 276

  Fly   691 RLCRDVPSERLGYQTGGIQDIKKHKWFLGFDWDGLASQLLIPPFVRPIAHPTDVRYFDR 749
            .|.:...|:|.|....|.:|||:|:||...:|..|.:|.:..|:|..|::|.|:..||:
  Fly   277 HLLQVDLSKRFGNLINGNRDIKEHEWFKDVEWIPLLNQTVNAPYVPNISNPEDISNFDK 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pkg21D	NP_477213.1	Crp	183..386	CDD:223736
		CAP_ED	185..285	CDD:237999
		CAP_ED	304..419	CDD:237999
		Pkinase	457..717	CDD:278497	104/261 (40%)
		STKc_cGK	463..724	CDD:270724	105/262 (40%)
		S_TK_X	719..>760	CDD:214529	10/31 (32%)
CG12069	NP_651819.1	PTZ00263	44..356	CDD:140289	118/298 (40%)
CG12069	NP_651819.1	PKc_like	45..335	CDD:304357	116/295 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440848
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24353
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940