DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pkg21D and CG14693

DIOPT Version :9

Sequence 1:	NP_477213.1	Gene:	Pkg21D / 33253	FlyBaseID:	FBgn0000442	Length:	768	Species:	Drosophila melanogaster
Sequence 2:	NP_001262467.1	Gene:	CG14693 / 41299	FlyBaseID:	FBgn0037837	Length:	586	Species:	Drosophila melanogaster

Alignment Length:	288	Identity:	62/288 - (21%)
Similarity:	108/288 - (37%)	Gaps:	61/288 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   260 TASIRVLSEAARVWVLDRRVFQQIMMCTGLQRIENSVNFLRSVPLLMNL-------------SEE 311
            :|.:|..|::..:...|:.:.:             :.:.:|::|..|.|             |.:
  Fly    52 SARVRTKSKSGFLTAADKSLIR-------------TPHVIRTIPERMKLCKLFAKLTCLAGFSPK 103

  Fly   312 LLAKIADVLELEFYAAGTYIIRQGTAGDSFFLISQGNVRVTQKLTPTSPEETELRTLSRGDYFGE 376
            :.|::..|:.|....||..||||..|..:.|.:..|.|.:.:.......|...:..|..||..|:
  Fly   104 IRARLVPVVRLMPVDAGRIIIRQSDAPITVFFVLTGEVHMIKNEKNQKGEGVVMGFLGAGDMMGD 168

  Fly   377 QALINEDKRTANIIALSPGVECLTLDRDSFKRLIGDLC---------ELKEKDYGDESRKLAMKQ 432
            ..|:...|||....| :...|.|.|....|..::|...         .||..||.|   .|...|
  Fly   169 VELLEGIKRTHTFRA-ATYCELLVLFDYDFAPILGAYMTKIWEEKKRALKALDYFD---FLDDDQ 229

  Fly   433 AQESCRDEPKEQLQQEFPDLKLTD-LEVVSTLGIGGFGRVELVKAHHQDRVDIFALKCLKKRHIV 496
            ..|:||          :..||..| |:.:....||....|..|.:.     :...|:||..:  |
  Fly   230 IVEACR----------YGRLKQFDPLDTIFCEDIGSMTNVHFVLSG-----ECLILQCLNIK--V 277

  Fly   497 DTKQEEHIFSERHIMLSSRSPFICRLYR 524
            ..|:.:.::.    :|.:....:.:::|
  Fly   278 TMKRGKKVYD----LLPASEGDVSKMFR 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pkg21D	NP_477213.1	Crp	183..386	CDD:223736	29/138 (21%)
		CAP_ED	185..285	CDD:237999	4/24 (17%)
		CAP_ED	304..419	CDD:237999	33/136 (24%)
		Pkinase	457..717	CDD:278497	12/68 (18%)
		STKc_cGK	463..724	CDD:270724	11/62 (18%)
		S_TK_X	719..>760	CDD:214529
CG14693	NP_001262467.1	Crp	90..>204	CDD:223736	29/114 (25%)
CG14693	NP_001262467.1	CAP_ED	97..204	CDD:237999	29/107 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0664
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900