DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pkg21D and Pka-C3

DIOPT Version :9

Sequence 1:	NP_477213.1	Gene:	Pkg21D / 33253	FlyBaseID:	FBgn0000442	Length:	768	Species:	Drosophila melanogaster
Sequence 2:	NP_730083.2	Gene:	Pka-C3 / 39733	FlyBaseID:	FBgn0000489	Length:	583	Species:	Drosophila melanogaster

Alignment Length:	346	Identity:	136/346 - (39%)
Similarity:	203/346 - (58%)	Gaps:	21/346 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   412 DLCELKEKDYGDESRKLAMKQAQESCRDEPKE----QLQQEFPDLKLTDLEVVSTLGIGGFGRVE 472
            |..|..|:|.|:|:       ..|...||.:|    |..:......|.|.:::.|:|.|.||||.
  Fly   232 DSSESIEEDDGNET-------DDEEDDDESEESSSVQTAKGVRKYHLDDYQIIKTVGTGTFGRVC 289

  Fly   473 LVKAHHQDRVD--IFALKCLKKRHIVDTKQEEHIFSERHIMLSSRSPFICRLYRTFRDEKYVYML 535
            |.:    ||:.  ..|:|.|....::..||.||:.:||:|:...|.||:..|..:.:|:..:||:
  Fly   290 LCR----DRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISLEWSTKDDSNLYMI 350

  Fly   536 LEACMGGEIWTMLRDRGSFEDNAAQFIIGCVLQAFEYLHARGIIYRDLKPENLMLDERGYVKIVD 600
            .:...|||::|.||:.|.|....:.|....::.|.||||:..|:|||||||||:::..|::||.|
  Fly   351 FDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITD 415

  Fly   601 FGFAKQIGTSSKTWTFCGTPEYVAPEIILNKGHDRAVDYWALGILIHELLNGTPPFSAPDPMQTY 665
            |||||::  ..:|||.||||||:|||||.:|||::|||:||||:||:|:|.|.|||....|...|
  Fly   416 FGFAKKL--RDRTWTLCGTPEYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIY 478

  Fly   666 NLILKGIDMIAFPKHISRWAVQLIKRLCRDVPSERLGYQTGGIQDIKKHKWFLGFDWDGLASQLL 730
            ..||.|  .|.:.:|:...|..|||:|..:..::|||....|..|:|:|:||...:|:.:.|:.|
  Fly   479 EKILSG--KIEWERHMDPIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWFKHLNWNDVYSKKL 541

  Fly   731 IPPFVRPIAHPTDVRYFDRFP 751
            .||.:..:.|..|.:.||.:|
  Fly   542 KPPILPDVHHDGDTKNFDDYP 562

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pkg21D	NP_477213.1	Crp	183..386	CDD:223736
		CAP_ED	185..285	CDD:237999
		CAP_ED	304..419	CDD:237999	2/6 (33%)
		Pkinase	457..717	CDD:278497	111/261 (43%)
		STKc_cGK	463..724	CDD:270724	113/262 (43%)
		S_TK_X	719..>760	CDD:214529	10/33 (30%)
Pka-C3	NP_730083.2	PTZ00263	262..583	CDD:140289	125/309 (40%)
Pka-C3	NP_730083.2	STKc_PRKX_like	272..563	CDD:270763	124/299 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440855
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24353
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940