Protein Alignment Pkg21D and prkg1a

DIOPT Version :10

• Sequence 1: NP_477213.1
• Gene: Pkg21D / 33253
• FlyBaseID: FBgn0000442
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: XP_073775545.1
• Gene: prkg1a / 394005
• ZFINID: ZDB-GENE-040426-1308
• Length: 700
• Species: Danio rerio
• Alignment Length: 781
• Identity: 370/781 - (47%)
• Similarity: 483/781 - (61%)
• Gaps: 116/781 - (14%)

  Fly     7 TDREREA---------IVSNLTKDVQAL----REMVRSRESELVKLHREIHKLKSVLQQTTNNLN 58
            :||:||.         .:|:|.:|...:    .|.:|..|..|::...||.:|
Zfish    17 SDRQRERRRIPVSTVNTMSDLDEDFAKILMLKEERIRDLERRLLEREDEISEL------------ 69

  Fly    59 VTRNEKAKKKLYSLPEQCGEQESRNQNPHLCSSCGMVLPTSPEFALEALSLGPLSPLASTSSASP 123
                   |:||                 |.|.|   |||::        .:||
Zfish    70 -------KRKL-----------------HKCQS---VLPSA--------QIGP------------ 87

  Fly   124 SGRTSADEVRPKAMPAAIKKQGVSAESCVQSMQQSYSIPIPKYEKDFSDKQQIKDAIMDNDFLKN 188
              ||.             :.||:|||.  |:.|...:....:..|....|..||.||:||||:||
Zfish    88 --RTH-------------RAQGISAEP--QTHQDLSNQSFRRVAKSDRSKDLIKSAILDNDFMKN 135

  Fly   189 IDASQVRELVDSMYSKSIAAGEFVIREGEVGAHLYVSAAGEFAVMQQGKVLDKMGAGKAFGELAI 253
            ::.||::|:||.||.........:|:||:||:.:||...|:..|.::|..|..||.||.||||||
Zfish   136 LEMSQIQEIVDCMYPVDYDKNSCIIKEGDVGSLVYVMEDGKVEVTKEGLKLCTMGPGKVFGELAI 200

  Fly   254 LYNCTRTASIRVLSEAARVWVLDRRVFQQIMMCTGLQRIENSVNFLRSVPLLMNLSEELLAKIAD 318
            ||||||||::|.:| :.::|.:||:.||.|||.|||.:....:..|:||.....|.||:|:|:||
Zfish   201 LYNCTRTATVRTVS-SVKLWAIDRQCFQTIMMRTGLIKHAEYMELLKSVLTFRGLPEEILSKLAD 264

  Fly   319 VLELEFYAAGTYIIRQGTAGDSFFLISQGNVRVTQKLTPTSPEETELRTLSRGDYFGEQALINED 383
            |||...|..|.||||||..||:||:||:|.|.:|::..| ..|...||::.|||.|||:||..||
Zfish   265 VLEETHYEDGNYIIRQGARGDTFFIISKGKVTMTREDCP-GQEPVYLRSMGRGDSFGEKALQGED 328

  Fly   384 KRTANIIALSPGVECLTLDRDSFKRLIGDLCELKEKDYGDESRKLAMKQAQESCRD-EPKEQLQQ 447
            .||||:|| :..|.||.:||||:|.|||.|.::..|                .|.| |.|.:.:.
Zfish   329 IRTANVIA-AETVTCLVIDRDSYKHLIGGLEDVSNK----------------GCEDAEAKAKYEA 376

  Fly   448 E---FPDLKLTDLEVVSTLGIGGFGRVELVKAHHQDRVDIFALKCLKKRHIVDTKQEEHIFSERH 509
            |   |.:|.|:|..::.|||:|||||||||:. ..|.:..||:|.|||||||||:|:|||.||:.
Zfish   377 ENAFFSNLNLSDFNIIDTLGVGGFGRVELVQL-KSDEMKTFAMKILKKRHIVDTRQQEHIRSEKL 440

  Fly   510 IMLSSRSPFICRLYRTFRDEKYVYMLLEACMGGEIWTMLRDRGSFEDNAAQFIIGCVLQAFEYLH 574
            ||..:.|.||.||||||:|.||:|||:|||:|||:||:|||||:|:|:..:|...||::||.|||
Zfish   441 IMQEAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGNFDDSTTRFYTACVVEAFAYLH 505

  Fly   575 ARGIIYRDLKPENLMLDERGYVKIVDFGFAKQIGTSSKTWTFCGTPEYVAPEIILNKGHDRAVDY 639
            ::||||||||||||:||.|||.|:|||||||:||...|||||||||||||||||||||||.:.||
Zfish   506 SKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADY 570

  Fly   640 WALGILIHELLNGTPPFSAPDPMQTYNLILKGIDMIAFPKHISRWAVQLIKRLCRDVPSERLGYQ 704
            |:||||::|||.|:||||.||||:|||:||:|||||.|||.|::.|..|||:||||.||||||..
Zfish   571 WSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKITKNAANLIKKLCRDTPSERLGNL 635

  Fly   705 TGGIQDIKKHKWFLGFDWDGLASQLLIPPFVRPIAHPTDVRYFDRFPCDLNE--PPDELSGWDAD 767
            ..|::||:|||||.||:||||....|:||.:..:...||...||.||.| ||  |||:.||||.|
Zfish   636 KNGVKDIQKHKWFEGFNWDGLRKGTLMPPIIPNVTSSTDTSNFDSFPED-NEDPPPDDNSGWDID 699

  Fly   768 F 768
            |
Zfish   700 F 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkg21D	NP_477213.1	CAP_ED	185..285	CDD:237999	47/99 (47%)
		CAP_ED	304..419	CDD:237999	59/114 (52%)
		STKc_cGK	463..724	CDD:270724	178/260 (68%)
		S_TK_X	719..>760	CDD:214529	20/42 (48%)
prkg1a	XP_073775545.1	None