Protein Alignment Pkg21D and prkg3

DIOPT Version :10

• Sequence 1: NP_477213.1
• Gene: Pkg21D / 33253
• FlyBaseID: FBgn0000442
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: XP_073790012.1
• Gene: prkg3 / 326020
• ZFINID: ZDB-GENE-030131-4745
• Length: 738
• Species: Danio rerio
• Alignment Length: 782
• Identity: 287/782 - (36%)
• Similarity: 423/782 - (54%)
• Gaps: 105/782 - (13%)

  Fly     6 LTDREREAIVSNLTKDVQALREMVRSRESELVKLHREIHKLKSVLQQTTN-NLNVTRN-EKAKKK 68
            |:|:...|:|.         ..::|..|::|.||.:.:.|...:.|:..| |.::.|. |..:|.
Zfish    43 LSDQCHAALVK---------LNLLRPMEAQLKKLRQMLEKECQLSQELKNQNQDLKRQLEHKEKH 98

  Fly    69 LYSLPEQ-----CGEQESRNQNPHLCSSCGMVLPTSPEFALEALSLGPLSPLASTSSASPSGRTS 128
            |.:|.|:     |..|.:.|:.|.:......|:  :||...|.|.:                  :
Zfish    99 LQALQERLDQLDCTTQRTSNELPKVWQGRAAVM--APEQVPEVLDI------------------T 143

  Fly   129 ADEVRPKAMPAAIKKQGVSAESCVQSMQQSYSIPIPKYEKDFSDKQQIKDAIMDNDFLKNIDASQ 193
            |:.|                                  :|..|:..||..||..||||:.:|..|
Zfish   144 ANRV----------------------------------QKTSSETSQIVKAIGKNDFLRRLDEEQ 174

  Fly   194 VRELVDSMYSKSIAAGEFVIREGEVGAHLYVSAAGEFAVMQQGKVLDKMGAGKAFGELAILYNCT 258
            :..:||.|......||:.:|:||..|..:|:.||||..|.|.|:.|..:..|..||||||||||.
Zfish   175 ISMMVDLMKVLDCRAGDEIIKEGTEGDSMYIVAAGELKVTQAGRDLRILSLGDMFGELAILYNCK 239

  Fly   259 RTASIRVLSEAARVWVLDRRVFQQIMMCTGLQRIENSVNFLRSVPLLMNLSEELLAKIADVLELE 323
            ||||::.:| |.::|.::|:.::.||......:.|..:.||::...|..|::..|:||.|.:|..
Zfish   240 RTASVKAIS-AVKLWCIERQTYRSIMTNKSKMKREQLMGFLKTARTLKALNDVQLSKIIDSMEEV 303

  Fly   324 FYAAGTYIIRQGTAGDSFFLISQGNVRVTQKLTPTSPEETELRTLSRGDYFGEQALINEDKRTAN 388
            .:.....|:|:|..|::|::|.:|.|.||:|:   :.::..:|.:..|::|||.|||.|..|||.
Zfish   304 RFQDNEVIVREGAEGNTFYIILKGEVLVTKKV---NGQQKTIRKMGEGEHFGELALIREILRTAT 365

  Fly   389 IIALSPGVECLTLDRDSFKRLIGDLCELKEKDYGDESRKLAMKQAQESCRDEPKEQLQQEFPDLK 453
            ..|:.. |.|.::|::.|:..|    ..:..:..|::....:.:..|..|.|         ..||
Zfish   366 CTAVGV-VICFSIDKEVFEETI----PFESLELHDDANVSEIDEKPEKARPE---------TSLK 416

  Fly   454 LTDLEVV-----------STLGIGGFGRVELVKA-HHQDRVDIFALKCLKKRHIVDTKQEEHIFS 506
            |.||..|           .||||||||:||||.. .|:   ..||:|.:.|:|:|..|||.||..
Zfish   417 LKDLVPVLYQEGSYQGDPVTLGIGGFGKVELVTTLEHR---KYFAMKRISKQHVVAKKQEAHILL 478

  Fly   507 ERHIMLSSRSPFICRLYRTFRDEKYVYMLLEACMGGEIWTMLRDRGSFEDNAAQFIIGCVLQAFE 571
            |:.|:...|..||.||:..|:|.:||||::|.|.||||||.|::.|.||:..|.||..||::|:.
Zfish   479 EKKILQGIRCDFIVRLHAAFKDSRYVYMIMEFCPGGEIWTKLKEAGRFEEKIAVFITACVVEAYA 543

  Fly   572 YLHARGIIYRDLKPENLMLDERGYVKIVDFGFAKQIGTSSKTWTFCGTPEYVAPEIILNKGHDRA 636
            |||.:||:||||||||||||.:||||:|||||||::....||::|||||||::||||.|:|||.|
Zfish   544 YLHNKGILYRDLKPENLMLDSKGYVKLVDFGFAKELSRGEKTYSFCGTPEYISPEIIQNQGHDIA 608

  Fly   637 VDYWALGILIHELLNGTPPFSAPDPMQTYNLILKGIDMIAFPKHISRWAVQLIKRLCRDVPSERL 701
            .|:|:||:||:|||.|:||||:.:|.:.|..||.|:  :.||.::...|..:|.:|||..|.:||
Zfish   609 ADFWSLGVLIYELLVGSPPFSSSEPQKIYAKILDGV--LNFPSYMGEGAKSIISKLCRLRPGQRL 671

  Fly   702 GYQTGGIQDIKKHKWFLGFDWDGLASQLLIPPFVRPIAHPTDVRYFDRFPCDLNEPPDELSGWDA 766
            |....||:|::.|:||...:|..|....|..|.||.|........|||||.|..:..:|.||||.
Zfish   672 GNTKNGIKDVRHHRWFNSINWHKLRMGQLEAPTVRLIRKGPCYINFDRFPYDKTQAEEEFSGWDC 736

  Fly   767 DF 768
            ||
Zfish   737 DF 738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkg21D	NP_477213.1	CAP_ED	185..285	CDD:237999	42/99 (42%)
		CAP_ED	304..419	CDD:237999	36/114 (32%)
		STKc_cGK	463..724	CDD:270724	137/261 (52%)
		S_TK_X	719..>760	CDD:214529	13/40 (33%)
prkg3	XP_073790012.1	None