Protein Alignment Pkg21D and Sgk2

DIOPT Version :10

• Sequence 1: NP_477213.1
• Gene: Pkg21D / 33253
• FlyBaseID: FBgn0000442
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: NP_038759.1
• Gene: Sgk2 / 27219
• MGIID: 1351318
• Length: 367
• Species: Mus musculus
• Alignment Length: 301
• Identity: 111/301 - (36%)
• Similarity: 175/301 - (58%)
• Gaps: 7/301 - (2%)

  Fly   450 PDLKLTDLEVVSTLGIGGFGRVELVKAHHQDRVDIFALKCLKKRHIVDTKQEEHIFSERHIMLSS 514
            |:.:.||.:.:..:|.|.:|:|.|.|......  .:|:|.|:|:.|:..|::.||.:||:::|.:
Mouse    28 PNARPTDFDFLKVIGKGNYGKVLLAKRKSDGA--FYAVKVLQKKSILKNKEQNHIMAERNVLLKN 90

  Fly   515 -RSPFICRLYRTFRDEKYVYMLLEACMGGEIWTMLRDRGSFEDNAAQFIIGCVLQAFEYLHARGI 578
             |.||:..|..:|:..:.:|.:|:...|||::..|:....|.:..|:|....|..|..|||:..|
Mouse    91 VRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYTAEVASAIGYLHSLNI 155

  Fly   579 IYRDLKPENLMLDERGYVKIVDFGFAKQ-IGTSSKTWTFCGTPEYVAPEIILNKGHDRAVDYWAL 642
            |||||||||::||.:|:|.:.|||..|: :.....|.||||||||:|||::..:.:|||||:|.|
Mouse   156 IYRDLKPENILLDCQGHVVLTDFGLCKECVEPEETTSTFCGTPEYLAPEVLRKEPYDRAVDWWCL 220

  Fly   643 GILIHELLNGTPPFSAPDPMQTYNLILKGIDMIAFPKHISRWAVQLIKRLCRDVPSERLGYQTGG 707
            |.:::|:|:|.|||...|..|.|..||.  ..:..|...:..|..|::.|......:|||.:...
Mouse   221 GAVLYEMLHGLPPFFNTDVAQMYENILH--QPLQIPGGRTVAACDLLQGLLHKDQRQRLGSKEDF 283

  Fly   708 IQDIKKHKWFLGFDWDGLASQLLIPPFVRPIAHPTDVRYFD 748
            : |||.|.:|...:||.|..:.|.|||...:..|.|:::||
Mouse   284 L-DIKNHMFFSPINWDDLYHKRLTPPFNPNVEGPADLKHFD 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkg21D	NP_477213.1	CAP_ED	185..285	CDD:237999
		CAP_ED	304..419	CDD:237999
		STKc_cGK	463..724	CDD:270724	98/262 (37%)
		S_TK_X	719..>760	CDD:214529	11/30 (37%)
Sgk2	NP_038759.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28		111/301 (37%)
		Protein Kinases, catalytic domain	39..359	CDD:473864	108/290 (37%)
		Nuclear localization signal. /evidence=ECO:0000250	68..78		3/9 (33%)