Protein Alignment Pkg21D and akt-2

DIOPT Version :10

• Sequence 1: NP_477213.1
• Gene: Pkg21D / 33253
• FlyBaseID: FBgn0000442
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: NP_510357.3
• Gene: akt-2 / 181524
• WormBaseID: WBGene00000103
• Length: 528
• Species: Caenorhabditis elegans
• Alignment Length: 328
• Identity: 111/328 - (33%)
• Similarity: 185/328 - (56%)
• Gaps: 19/328 - (5%)

  Fly   439 DEPKEQLQQEFPDLKLTDLEVVSTLGIGGFGRVELVKAHHQDRVDIFALKCLKKRHIVDTKQEEH 503
            |||:|..::.  .:.:.|.:.:..||.|.||:|.|.:....|:  ::|:|.::|..:||..:..|
 Worm   164 DEPEEVPRKN--TVTMDDFDFLKVLGQGTFGKVILCREKSSDK--LYAIKIIRKEMVVDRSEVAH 224

  Fly   504 IFSERHIMLSSRSPFICRLYRTFRDEKYVYMLLEACMGGEIWTMLRDRGSFEDNAAQFIIGCVLQ 568
            ..:|..::.:...||:..|..:|:.:.::..::|...|||::|.|:...:|.:...:|....::.
 Worm   225 TLTENRVLYACVHPFLTLLKYSFQAQYHICFVMEFANGGELFTHLQRCKTFSEARTRFYGSEIIL 289

  Fly   569 AFEYLHARGIIYRDLKPENLMLDERGYVKIVDFGFAK-QIGTSSKTWTFCGTPEYVAPEIILNKG 632
            |..|||.|.|:|||:|.|||:||..|::||.|||..| :|....||.||||||||:|||:|.:..
 Worm   290 ALGYLHHRNIVYRDMKLENLLLDRDGHIKITDFGLCKEEIKYGDKTSTFCGTPEYLAPEVIEDID 354

  Fly   633 HDRAVDYWALGILIHELLNGTPPFSAPDPMQTYNLI----LKGIDMIAFPKHISRWAVQLIKRLC 693
            :||:||:|.:|::::|::.|..||||.:..:.:.||    ||      ||..:|..||.|:..|.
 Worm   355 YDRSVDWWGVGVVMYEMMCGRLPFSAKENGKLFELITTCDLK------FPNRLSPEAVTLLSGLL 413

  Fly   694 RDVPSERLGYQTGGIQDIKKHKWFLGFDWDGLASQLLIPPFVRPIAHPTDVRYFDR----FPCDL 754
            ..||::|||......:::.:.::|...||:....:.:.|||...:...||..:|||    .|..|
 Worm   414 ERVPAKRLGAGPDDAREVSRAEFFKDVDWEATLRKEVEPPFKPNVMSETDTSFFDREFTSMPVQL 478

  Fly   755 NEP 757
            ..|
 Worm   479 TPP 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkg21D	NP_477213.1	CAP_ED	185..285	CDD:237999
		CAP_ED	304..419	CDD:237999
		STKc_cGK	463..724	CDD:270724	95/265 (36%)
		S_TK_X	719..>760	CDD:214529	13/43 (30%)
akt-2	NP_510357.3	PH_PKB	11..116	CDD:269947
		Protein Kinases, catalytic domain	184..509	CDD:473864	106/306 (35%)