Protein Alignment Pkg21D and akt-1

DIOPT Version :10

• Sequence 1: NP_477213.1
• Gene: Pkg21D / 33253
• FlyBaseID: FBgn0000442
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: NP_001023646.1
• Gene: akt-1 / 179424
• WormBaseID: WBGene00000102
• Length: 546
• Species: Caenorhabditis elegans
• Alignment Length: 459
• Identity: 131/459 - (28%)
• Similarity: 220/459 - (47%)
• Gaps: 72/459 - (15%)

  Fly   319 VLELEFYAAGTYIIRQGTAGDSFFLISQGNVRVTQKLTPTSPEETELRTLSRGDYFGEQALINED 383
            |:|..|||....:.::       ::.:..::....|.|..:|:|..:.|       .:|..|:||
 Worm    93 VIERTFYAESAEVRQR-------WIHAIESISKKYKGTNANPQEELMET-------NQQPKIDED 143

  Fly   384 KR---TANIIALSP----GVECLTLDRDSFKRLIGDLCELKEKDYGDESRKLAMKQAQESCRDEP 441
            ..   .|:.|...|    |..| ::|..:....|.|..|..::|      |:.|:
 Worm   144 SEFAGAAHAIMGQPSSGHGDNC-SIDFRASMISIADTSEAAKRD------KITME---------- 191

  Fly   442 KEQLQQEFPDLKLTDLEVVSTLGIGGFGRVELVKAHHQDRVDIFALKCLKKRHIVDTKQEEHIFS 506
                          |.:.:..||.|.||:|.|.|.....:  ::|:|.|||..|:..::..|..:
 Worm   192 --------------DFDFLKVLGKGTFGKVILCKEKRTQK--LYAIKILKKDVIIAREEVAHTLT 240

  Fly   507 ERHIMLSSRSPFICRLYRTFRDEKYVYMLLEACMGGEIWTMLR-----DRGSFEDNAAQFIIGCV 566
            |..::...:.||:..|..:|:....:..::|..:||:::..|.     ::..|.:..|:|....:
 Worm   241 ENRVLQRCKHPFLTELKYSFQTNDRLCFVMEFAIGGDLYYHLNREVQMNKEGFSEPRARFYGSEI 305

  Fly   567 LQAFEYLHARGIIYRDLKPENLMLDERGYVKIVDFGFAK-QIGTSSKTWTFCGTPEYVAPEIILN 630
            :.|..||||..|:|||||.|||:||:.|::||.|||..| :|....||.||||||||:|||::.:
 Worm   306 VLALGYLHANSIVYRDLKLENLLLDKDGHIKIADFGLCKEEISFGDKTSTFCGTPEYLAPEVLDD 370

  Fly   631 KGHDRAVDYWALGILIHELLNGTPPFSAPDPMQTYNLILKGIDMIAFPKHISRWAVQLIKRLCRD 695
            ..:.|.||:|.:|::::|::.|..||.:.|..:.:.||:.|  .:.||..:|:.|..|:..|...
 Worm   371 HDYGRCVDWWGVGVVMYEMMCGRLPFYSKDHNKLFELIMAG--DLRFPSKLSQEARTLLTGLLVK 433

  Fly   696 VPSERLGYQTGGIQD---IKKHKWFLGFDWDGLASQLLIPPFVRPIAHPTDVRYFDR----FPCD 753
            .|::|||   ||.:|   |.:..:|...||:....:.:.||:...:...||..|||.    .|..
 Worm   434 DPTQRLG---GGPEDALEICRADFFRTVDWEATYRKEIEPPYKPNVQSETDTSYFDNEFTSQPVQ 495

  Fly   754 LNEP 757
            |..|
 Worm   496 LTPP 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkg21D	NP_477213.1	CAP_ED	185..285	CDD:237999
		CAP_ED	304..419	CDD:237999	23/106 (22%)
		STKc_cGK	463..724	CDD:270724	94/269 (35%)
		S_TK_X	719..>760	CDD:214529	12/43 (28%)
akt-1	NP_001023646.1	PH_PKB	14..121	CDD:269947	5/34 (15%)
		STKc_PKB	197..525	CDD:270723	104/310 (34%)