Protein Alignment Pkg21D and for

DIOPT Version :10

• Sequence 1: NP_477213.1
• Gene: Pkg21D / 33253
• FlyBaseID: FBgn0000442
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: XP_061515455.1
• Gene: for / 1279830
• VectorBaseID: AGAMI1_003945
• Length: 1074
• Species: Anopheles gambiae
• Alignment Length: 670
• Identity: 327/670 - (48%)
• Similarity: 449/670 - (67%)
• Gaps: 39/670 - (5%)

  Fly   111 PLSPLASTSSASPSGRTSADEVRPKAMPAAIKK----QGVSAESCVQSMQQSYSIPIPKYEKDFS 171
            |||.::|:||||.|..:|:..       ::.||    .|.|:.:..:|...|.:.....:::
Mosquito   432 PLSSMSSSSSASSSPPSSSKS-------SSFKKLFGGAGSSSSNGSRSTSNSSTGSGTVHQQ--- 486

  Fly   172 DKQQIKDAIMDNDFLKNIDAS--QVRELVD-SMYSKSIAAGEFVIREGEVG--AHLYVSA-AGEF 230
            .:||:.|...|...:....||  :...||. ..|::....|..:..|...|  ..:|.:. .|..
Mosquito   487 RRQQLGDDCSDAYIIATRPASGGKYPSLVPVHTYARKRRTGNLIANEPIYGNVEEIYANPDEGRV 551

  Fly   231 AVMQQGKVLDKMGAGKAFGELAILYNCTRTASIRVLSEAARVWVLDRRVFQQIMMCTGLQRIENS 295
            .|.::||.|..:...|..|||||||:|.|||:|...:: .::|.::|:.||.|||.|||.|....
Mosquito   552 EVSREGKYLSTLSGAKVLGELAILYHCQRTATITAATD-CKLWAIERQCFQTIMMRTGLIRQAEY 615

  Fly   296 VNFLRSVPLLMNLSEELLAKIADVLELEFYAAGTYIIRQGTAGDSFFLISQGNVRVTQKLTPTSP 360
            .:||:|||:..||.|:.|.||:||||..:|..|.||||||..||:||:||:|.||||.: .|.:.
Mosquito   616 SDFLKSVPIFKNLPEDTLCKISDVLEECYYQKGDYIIRQGARGDTFFIISKGQVRVTIR-QPDTQ 679

  Fly   361 EETELRTLSRGDYFGEQALINEDKRTANIIALSP-GVECLTLDRDSFKRLIGDLCELKEKDYGDE 424
            ||..:|||.:||:|||:||..:|.||||||..|| ||.||.:|||:|.:||.:|.|::.: |.||
Mosquito   680 EEKFIRTLGKGDFFGEKALQGDDLRTANIICDSPEGVTCLVIDRDTFNQLISNLDEIRNR-YNDE 743

  Fly   425 SRKLAMKQAQESCRDEPKEQLQQEFPDLKLTDLEVVSTLGIGGFGRVELVKAHHQDRVDIFALKC 489
                .:.|         ::::.:||.::||:||.|:||||:|||||||||:. .||:...||||.
Mosquito   744 ----GVSQ---------RKKIWEEFREVKLSDLRVISTLGVGGFGRVELVQL-AQDKSRSFALKQ 794

  Fly   490 LKKRHIVDTKQEEHIFSERHIMLSSRSPFICRLYRTFRDEKYVYMLLEACMGGEIWTMLRDRGSF 554
            :||..||:|:|::||.||:.||..:.|.||.:||:||:|.||:|||:|:|:|||:||:|||||.|
Mosquito   795 MKKAQIVETRQQQHIMSEKEIMSEANSDFIVKLYKTFKDRKYLYMLMESCLGGELWTILRDRGHF 859

  Fly   555 EDNAAQFIIGCVLQAFEYLHARGIIYRDLKPENLMLDERGYVKIVDFGFAKQIGTSSKTWTFCGT 619
            :|...:|...||::||:|||:|.|||||||||||:||..||||:|||||||::.:..||||||||
Mosquito   860 DDGTTRFYTACVVEAFDYLHSRNIIYRDLKPENLLLDVSGYVKLVDFGFAKKLQSGRKTWTFCGT 924

  Fly   620 PEYVAPEIILNKGHDRAVDYWALGILIHELLNGTPPFSAPDPMQTYNLILKGIDMIAFPKHISRW 684
            |||||||:|||:|||.:.|||:||:|:.|||.|||||:..|||:|||:||||||.|.||::|:|.
Mosquito   925 PEYVAPEVILNRGHDISADYWSLGVLMFELLTGTPPFTGADPMRTYNIILKGIDAIEFPRNITRN 989

  Fly   685 AVQLIKRLCRDVPSERLGYQTGGIQDIKKHKWFLGFDWDGLASQLLIPPFVRPIAHPTDVRYFDR 749
            |..|||:||||.|:||||||.|||.:|:|||||.||.|:||.::.|.||.:..:....|...||.
Mosquito   990 ASALIKKLCRDNPTERLGYQRGGISEIQKHKWFDGFYWEGLRNRSLPPPILPKVQSVVDTANFDD 1054

  Fly   750 FPCDLN-EPPDELSGWDADF 768
            :|.|.: .|||:|||||.||
Mosquito  1055 YPADPDGPPPDDLSGWDDDF 1074

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkg21D	NP_477213.1	CAP_ED	185..285	CDD:237999	32/105 (30%)
		CAP_ED	304..419	CDD:237999	63/115 (55%)
		STKc_cGK	463..724	CDD:270724	168/260 (65%)
		S_TK_X	719..>760	CDD:214529	15/41 (37%)
for	XP_061515455.1	None