Protein Alignment Pkg21D and Pkg21D

DIOPT Version :10

• Sequence 1: NP_477213.1
• Gene: Pkg21D / 33253
• FlyBaseID: FBgn0000442
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: XP_061512039.1
• Gene: Pkg21D / 1275446
• VectorBaseID: AGAMI1_000949
• Length: 1270
• Species: Anopheles gambiae
• Alignment Length: 768
• Identity: 490/768 - (63%)
• Similarity: 581/768 - (75%)
• Gaps: 42/768 - (5%)

  Fly    16 SNLTKDVQALREMVRSRESELVKLHREIHKLKSVLQQ-TTNNLNVTRNEKAKKKLYSLPEQCGEQ 79
            ::|.:::..||.::|:|:.|:.||.|||.|||||||| ..|:|..|.....:::| :|....|..
Mosquito   530 NSLEEELVGLRRLLRARDDEIDKLRREIDKLKSVLQQKAINSLEQTSIPSGQQRL-TLTSPAGTP 593

  Fly    80 ESRNQNPHLCSSCGMVLPTSPEFALEALSLGPLSPLASTSS--------ASPSGRTSADEVRPKA 136
            ..:.|  |:..  |.:|  |...|..|::..|||.|...|.        .|..|.|.
Mosquito   594 SHKGQ--HVAE--GELL--SSIQANYAMAGQPLSELFGISGNSFKLHQMKSVKGITL-------- 644

  Fly   137 MPAAIKKQGVSAESCVQSMQQSYSIPIPKYEKDFSDKQQIKDAIMDNDFLKNIDASQVRELVDSM 201
              .|:||||||.|||.....||..|.||||:||||.||.||||||:|||.||||:.|:||:||||
Mosquito   645 --QAMKKQGVSGESCDLMGSQSSDIKIPKYKKDFSAKQLIKDAIMENDFFKNIDSLQIREIVDSM 707

  Fly   202 YSKSIAAGEFVIREGEVGAHLYVSAAGEFAVMQQGKVLDKMGAGKAFGELAILYNCTRTASIRVL 266
            ||:....||:||.|||.|:||||||||||.|::..|||..||.|:||||||||||||||||||||
Mosquito   708 YSREFRKGEYVIHEGEAGSHLYVSAAGEFEVIKDSKVLGVMGPGRAFGELAILYNCTRTASIRVL 772

  Fly   267 SEAARVWVLDRRVFQQIMMCTGLQRIENSVNFLRSVPLLMNLSEELLAKIADVLELEFYAAGTYI 331
            .: :|||||||||||||||.||:||||.:||||:|||||.:||.::|.|||||||:|||.||.:|
Mosquito   773 CD-SRVWVLDRRVFQQIMMRTGMQRIEENVNFLKSVPLLKHLSNDVLTKIADVLEVEFYPAGAFI 836

  Fly   332 IRQGTAGDSFFLISQGNVRVTQKLTPTSPEETELRTLSRGDYFGEQALINEDKRTANIIALSPGV 396
            ||||.|||:|||||||.|:|||:|...|.|| |:|.|.||:||||||||.||||||||||:||||
Mosquito   837 IRQGAAGDTFFLISQGTVKVTQRLPGRSVEE-EIRILVRGEYFGEQALIREDKRTANIIAMSPGV 900

  Fly   397 ECLTLDRDSFKRLIGDLCELKEKDYGDESRKLAMKQAQE------SCRDEPKEQLQQEFPDLKLT 455
            |||||||:||.:.|||||||:||:||||.|.||.:..:.      ||        |.|..|:.||
Mosquito   901 ECLTLDRESFTKHIGDLCELQEKNYGDEERVLAFRNLENTHPSLGSC--------QPELMDVNLT 957

  Fly   456 DLEVVSTLGIGGFGRVELVKAHHQDRVDIFALKCLKKRHIVDTKQEEHIFSERHIMLSSRSPFIC 520
            |||||.|||:||||||||||........::||||:||||||||:|:||::|||.|||:.:|||||
Mosquito   958 DLEVVGTLGVGGFGRVELVKLERNGDTKVYALKCMKKRHIVDTRQQEHMYSERKIMLACQSPFIC 1022

  Fly   521 RLYRTFRDEKYVYMLLEACMGGEIWTMLRDRGSFEDNAAQFIIGCVLQAFEYLHARGIIYRDLKP 585
            |||||::|.|:||||||||||||:||:||||.:|||:.|:||:.||||||::||||||:||||||
Mosquito  1023 RLYRTYKDAKFVYMLLEACMGGEVWTILRDRVTFEDSTAKFIVACVLQAFDFLHARGIVYRDLKP 1087

  Fly   586 ENLMLDERGYVKIVDFGFAKQIGTSSKTWTFCGTPEYVAPEIILNKGHDRAVDYWALGILIHELL 650
            |||:||.|||.|:|||||:|.||.||||||||||||||||||||||||||:||||||||||||||
Mosquito  1088 ENLLLDARGYAKLVDFGFSKFIGYSSKTWTFCGTPEYVAPEIILNKGHDRSVDYWALGILIHELL 1152

  Fly   651 NGTPPFSAPDPMQTYNLILKGIDMIAFPKHISRWAVQLIKRLCRDVPSERLGYQTGGIQDIKKHK 715
            .|.|||:|.|||:|||:|||||||:.||||:||.||.|||||||||||||||||.||:|||||||
Mosquito  1153 TGIPPFTAADPMKTYNIILKGIDMVNFPKHMSRAAVSLIKRLCRDVPSERLGYQRGGVQDIKKHK 1217

  Fly   716 WFLGFDWDGLASQLLIPPFVRPIAHPTDVRYFDRFPCDLNEPPDELSGWDADF 768
            ||.|||||||.:..|..|....:..|.|:..||.||.||:.||||||||||||
Mosquito  1218 WFQGFDWDGLIALTLKSPLQPNLLGPLDMSNFDIFPKDLDIPPDELSGWDADF 1270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkg21D	NP_477213.1	CAP_ED	185..285	CDD:237999	72/99 (73%)
		CAP_ED	304..419	CDD:237999	83/114 (73%)
		STKc_cGK	463..724	CDD:270724	202/260 (78%)
		S_TK_X	719..>760	CDD:214529	19/40 (48%)
Pkg21D	XP_061512039.1	None