Protein Alignment Pkg21D and dmpk

DIOPT Version :10

• Sequence 1: NP_477213.1
• Gene: Pkg21D / 33253
• FlyBaseID: FBgn0000442
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: XP_004917016.2
• Gene: dmpk / 100491375
• XenbaseID: XB-GENE-949801
• Length: 587
• Species: Xenopus tropicalis
• Alignment Length: 335
• Identity: 96/335 - (28%)
• Similarity: 173/335 - (51%)
• Gaps: 33/335 - (9%)

  Fly   440 EPKEQLQQEFPDLKLTDLEVVSTLGIGGFGRVELVKAHHQDRVDIFALKCLKKRHIVDTKQEEHI 504
            :|..||.:| ..:|.:|.:::..:|.|.|..|.:|:.....:|  :|:|.:.|..::........
 Frog    46 DPLAQLIRE-QRMKRSDFDILKVIGRGAFSEVAVVRKKSNSQV--YAMKIMNKWDLLKRSDVACY 107

  Fly   505 FSERHIMLSSRSPFICRLYRTFRDEKYVYMLLEACMGGEIWTML-RDRGSFEDNAAQFIIGCVLQ 568
            ..||.::::....:|.:|:..|:|:.|:|::::..:||::.::| :....|..:.|.|.:..::.
 Frog   108 RQERDVLVNGDKRWITQLHFAFQDDNYLYLIMDYYVGGDLLSLLSKFSDGFPSHMAVFYLAEMVM 172

  Fly   569 AFEYLHARGIIYRDLKPENLMLDERGYVKIVDFGFAKQI---GTSSKTWTFCGTPEYVAPEIILN 630
            |...:|:.|.::||:||:|::|:..|::::.|||...::   ||.|.: ...|||:|::|||:|
 Frog   173 AISSVHSLGFVHRDIKPDNMLLNCAGHIRLGDFGSCLKLRGDGTVSSS-IAVGTPDYLSPEILL- 235

  Fly   631 KGHDRAV-----------DYWALGILIHELLNGTPPFSAPDPMQTYNLILKGIDMIAFP---KHI 681
                 ||           |:|:||:..:|:..|..||.|...::||..|:...:...||   ..:
 Frog   236 -----AVEDPTLCYGVECDWWSLGVCAYEMYFGYTPFYADLVVETYGKIIHFKEHFIFPPSSSEV 295

  Fly   682 SRWAVQLIKRLCRDVPSERLGYQTGGIQDIKKHKWFLGFDWDGLASQLLIPPFVRPIAHPTDVRY 746
            |..|:..|..|..| ...|||  .||:||.:.|..|.|.:|:.|...  |||:|......||...
 Frog   296 SSEALSFISSLICD-RETRLG--RGGLQDFQMHPLFAGIEWERLMDS--IPPYVPESEGATDTSN 355

  Fly   747 FDRFPCDLNE 756
            ||.....|:|
 Frog   356 FDMVEDQLSE 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkg21D	NP_477213.1	CAP_ED	185..285	CDD:237999
		CAP_ED	304..419	CDD:237999
		STKc_cGK	463..724	CDD:270724	79/278 (28%)
		S_TK_X	719..>760	CDD:214529	13/38 (34%)
dmpk	XP_004917016.2	Protein Kinases, catalytic domain	60..395	CDD:473864	91/320 (28%)