Protein Alignment Pkg21D and prkg2

DIOPT Version :10

• Sequence 1: NP_477213.1
• Gene: Pkg21D / 33253
• FlyBaseID: FBgn0000442
• Length: 768
• Species: Drosophila melanogaster
• Sequence 2: XP_021331649.2
• Gene: prkg2 / 100125912
• ZFINID: ZDB-GENE-060531-80
• Length: 769
• Species: Danio rerio
• Alignment Length: 784
• Identity: 368/784 - (46%)
• Similarity: 491/784 - (62%)
• Gaps: 55/784 - (7%)

  Fly    17 NLTKDVQALREMVRSRESELVK--LHREIHKLKSVLQQTTNNLNVTRNEKAKK-KLYSLPEQCGE 78
            |..|.|....:...:.||.||.  |...:.:|::.|::...:||      ||: ::..|.||..:
Zfish     9 NPLKQVSGSAKSKNNGESSLVPQVLRVRVEELETHLKKKDEDLN------AKELQIKHLEEQLAQ 67

  Fly    79 QES--RNQNPHLCSSCGMVLPTSPEFALEA---LSLGPLSPLASTSSASPSGRTSADEVRPKAMP 138
            |:.  ...:..|.|.|..:  ...:.||::   |.|.| |||....|...:|.......|.|.
Zfish    68 QKQTLSEISDTLRSKCLQL--NKLQDALKSQGELGLLP-SPLKEKVSQGLTGLLRETLNRRKG-- 127

  Fly   139 AAIKKQGVSAESCVQSMQQSYSIPIPKYE-------KDFSDKQQIKDAIMDNDFLKNIDASQVRE 196
               .|.|||||...::...|   .|||:.       |:.|.|:.:.||:..|.:|:.::..||::
Zfish   128 ---AKAGVSAEPSSRTYDSS---GIPKFYFESARVWKEQSVKKLLTDALNKNQYLRRLEVQQVKD 186

  Fly   197 LVDSMYSKSIAAGEFVIREGEVGAHLYVSAAGEFAVMQQGKVLDKMGAGKAFGELAILYNCTRTA 261
            :|:.||.::...||:||::||.|.||:|.|.|:..|.|..|:|..:.....||||||||||||||
Zfish   187 MVECMYERTYQQGEYVIKQGEPGNHLFVLADGKLDVYQHNKLLTSIAVWTTFGELAILYNCTRTA 251

  Fly   262 SIRVLSEAARVWVLDRRVFQQIMMCTGLQRIENSVNFLRSVPLLMNLSEELLAKIADVLELEFYA 326
            |::..|. .:.|.|||.||..||..|...|.|...||||||.||.:|..:.|.||.|.||:|:|.
Zfish   252 SVKAASN-VKTWALDREVFHNIMRMTAEARHEQYRNFLRSVSLLASLPGDKLTKIVDCLEVEYYN 315

  Fly   327 AGTYIIRQGTAGDSFFLISQGNVRVTQKLTPTSPEETELRTLSRGDYFGEQALINEDKRTANIIA 391
            .|.||||:|..|::|::|:.|.::|||. |....|...:.||.:||||||:|||::|.|:|||||
Zfish   316 KGDYIIREGEEGNTFYIIANGKIKVTQS-TQDHEEPQIINTLGKGDYFGEKALISDDVRSANIIA 379

  Fly   392 LSPGVECLTLDRDSFKRLIGDLCELKE--KDYGD----ESRKLAMKQAQESCRDEPKEQLQQEFP 450
            ...|||||.:||::|.:.:|...|||:  :.|.|    :.:|...|:: .|| ..|...:..:..
Zfish   380 EEDGVECLVIDRETFSQTVGTFDELKKYLQSYVDSLARDDKKRNAKRS-GSC-TPPNTPVSHDMI 442

  Fly   451 DLK-----------LTDLEVVSTLGIGGFGRVELVKAHHQDRVDIFALKCLKKRHIVDTKQEEHI 504
            :||           .|.||.::|||:||||||||||..:::..  |||||:|||||||.:|||||
Zfish   443 ELKERESSFASTIPFTCLEAIATLGVGGFGRVELVKLKNENVT--FALKCIKKRHIVDNRQEEHI 505

  Fly   505 FSERHIMLSSRSPFICRLYRTFRDEKYVYMLLEACMGGEIWTMLRDRGSFEDNAAQFIIGCVLQA 569
            :|||.|:|.:..|||.::|||::|.||||||||||:|||||::||||||||:..|:|.:|||.:|
Zfish   506 YSERRILLETNCPFIVKMYRTYKDNKYVYMLLEACLGGEIWSLLRDRGSFEEYTAKFCVGCVTEA 570

  Fly   570 FEYLHARGIIYRDLKPENLMLDERGYVKIVDFGFAKQIGTSSKTWTFCGTPEYVAPEIILNKGHD 634
            |||||..|||||||||||||||..||||:|||||||::....:|||||||||||||||||||||.
Zfish   571 FEYLHNNGIIYRDLKPENLMLDTDGYVKLVDFGFAKKLKCGQRTWTFCGTPEYVAPEIILNKGHG 635

  Fly   635 RAVDYWALGILIHELLNGTPPFSAPDPMQTYNLILKGIDMIAFPKHISRWAVQLIKRLCRDVPSE 699
            .:||:|:|||||.|||.|:|||:..|.|..|..|||||:.:.|||.|::....||::|||..|||
Zfish   636 LSVDFWSLGILIFELLTGSPPFTGSDQMIIYTFILKGIEKMDFPKKITKRPGDLIRKLCRQNPSE 700

  Fly   700 RLGYQTGGIQDIKKHKWFLGFDWDGLASQLLIPPFVRPIAHPTDVRYFDRFPCDLNEPPDELSGW 764
            |||....||.|||||:||.||.|.||.::.||.|..|.:..|||..|||.:|.:...||||:|||
Zfish   701 RLGNLKNGITDIKKHRWFTGFSWSGLKARNLISPLKREVKGPTDHSYFDSYPPEEEIPPDEMSGW 765

  Fly   765 DADF 768
            |.||
Zfish   766 DTDF 769

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkg21D	NP_477213.1	CAP_ED	185..285	CDD:237999	45/99 (45%)
		CAP_ED	304..419	CDD:237999	56/116 (48%)
		STKc_cGK	463..724	CDD:270724	172/260 (66%)
		S_TK_X	719..>760	CDD:214529	18/40 (45%)
prkg2	XP_021331649.2	None