DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3544 and CG11594

DIOPT Version :9

Sequence 1:	NP_001259842.1	Gene:	CG3544 / 33252	FlyBaseID:	FBgn0031279	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	NP_001261391.1	Gene:	CG11594 / 38473	FlyBaseID:	FBgn0035484	Length:	548	Species:	Drosophila melanogaster

Alignment Length:	522	Identity:	100/522 - (19%)
Similarity:	168/522 - (32%)	Gaps:	194/522 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 QITESAFELTRT----PTWRDSSTD------VQVREMEHTVGGPAELSKITG----SRAYTRFTG 178
            ::.|.|.:..:|    |.:.:.|:|      .||  ::..:|| .:.||:.|    :.......|
  Fly    27 RVLEQAVQTIQTWNPEPGYYNQSSDNIWQSICQV--VKKVIGG-VDKSKVKGIGFDATCSLVVLG 88

  Fly   179 PQIRKVYTQCPEQYERT----------SRISLISSFLASLL--IGGIASIDYSDGSGMNLLDIRK 231
            ||...:......:.|:.          .....|::|..|||  :||..|::         :::.|
  Fly    89 PQGSPLTVSKSGEAEQNIILWMDHRAEQETQEINAFKHSLLKYVGGQVSLE---------MEVPK 144

  Fly   232 KKWSAACLDACAPDLARRLMKPIPSSRLQGRIGDYY---------------------VKRWNFRP 275
            ..|           |.|.|      |:..|.|...:                     |.:||:.
  Fly   145 LLW-----------LKRNL------SQTFGNIWRVFDLPDFLTWRATGVDTRSLCSVVCKWNYD- 191

  Fly   276 DCMVVASTGS------KASELAGLLVENDFLMLSLD----------------------TSDVVVM 312
                 |:.||      |.::|.. |.:|:|..|..|                      ::..||
  Fly   192 -----AANGSWNKEFLKQADLEE-LTQNNFEKLGSDVQPPGRTVGKGLTAKAAGELGLSAGTVV- 249

  Fly   313 PLKKAPRLEDGHV------MCHPTR---RDEYMGLLCFQNG------GLTRKAICEDVAGGSWRH 362
                :..|.|.|.      .|....   .|:..|.:....|      .:|||| |  .|.|.|..
  Fly   250 ----STSLIDAHAGALGMFGCRSKESKGADDVQGKMALIAGTSTCHMSITRKA-C--FAQGVWGP 307

  Fly   363 FYEMLDATPSG---NNG--NVAVHFRD--------------------------REIIP------- 389
            :.   ||...|   |.|  ::|.|..|                          .:::|
  Fly   308 YQ---DAIIPGYFLNEGGQSIAGHLLDHVLKSHESYAELKSQLGEDKFIYQHLNKLLPELAAARG 369

  Fly   390 -TAKGTLRWDAHI--------SPMSAECIRGL-----HRFSTPEIEVRALIEGQIMHHWS---IA 437
             :..|.|..|.|:        ||::...:||:     ....|..:.::.|...|.:.:.:   |.
  Fly   370 LSQVGCLTQDVHVWPDLHGNRSPIADPTLRGVITGLDMTRGTESLAIKYLAFVQALAYGTRHIIE 434

  Fly   438 HEMGFHHTPNTKIIVVGEDSRCQSVLQIVADIFNAPVYQRTGVEVSLLGCAF--RARYAFYEHRE 500
            :...:...|...::..|..::....:|..|||.|.|.......|:.|:|.|.  .|....::..|
  Fly   435 NLYQYGRAPFQTLLFCGGLAKNPLYVQCHADICNLPALIPDEQEMVLVGAAALGAAASGHFDSLE 499

  Fly   501 SA 502
            ||
  Fly   500 SA 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3544	NP_001259842.1	FGGY_D-XK_euk	13..493	CDD:212660	97/511 (19%)
CG3544	NP_001259842.1	XylB	15..494	CDD:273550	97/512 (19%)
CG11594	NP_001261391.1	FGGY_YpCarbK_like	5..540	CDD:212663	100/522 (19%)
CG11594	NP_001261391.1	5C_CHO_kinase	6..540	CDD:273552	100/522 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45443085
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930