DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3544 and SPCPJ732.02c

DIOPT Version :9

Sequence 1:	NP_001259842.1	Gene:	CG3544 / 33252	FlyBaseID:	FBgn0031279	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	NP_001342982.1	Gene:	SPCPJ732.02c / 2539441	PomBaseID:	SPCPJ732.02c	Length:	555	Species:	Schizosaccharomyces pombe

Alignment Length:	517	Identity:	158/517 - (30%)
Similarity:	259/517 - (50%)	Gaps:	58/517 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 YLGLHLGTQLFRALILDSKLNVTYVAQIRYDVDLPEFKTTNGILSDGGPGEFLANPVMWVKALDM 78
            :|||.|.||..:.:::|..|||.....:.:|.||.::.|..|:..:|  .|..|...||:.|:|:
pombe     2 FLGLDLSTQQLKGVVIDESLNVHQEVAVDFDRDLSDYNTIKGVYRNG--YEVFAPVCMWLDAIDL 64

  Fly    79 LMDCLVKQGADMHTVVSIAGAAQQHGCVFWSELGLRRLCNLNVNLRLHEQITESAFELTRTPTWR 143
            |.:.| |...|:..:.:|:||.|||..||..:...:.|.:|:....|.:|: ||....| :|.|:
pombe    65 LFERL-KASVDVSKIQAISGAGQQHASVFLLKGSKKALNSLDAKSSLKQQL-ESLIHPT-SPNWQ 126

  Fly   144 DSSTDVQVREMEHTVGGPAELSKITGSRAYTRFTGPQIRKVYTQCPEQYERTSRISLISSFLASL 208
            |:||..:..|:|..:||...|:.:|||:|:.|||||||::.....||.||.|.||:|:|:||||:
pombe   127 DASTTKECEELESCIGGAKALADLTGSKAHLRFTGPQIKRFRRLHPETYENTERIALVSNFLASV 191

  Fly   209 LIGGIASIDYSDGSGMNLLDIRKKKWSAACLDACA-----PDLARRL-MKPIPSSRLQGRIGDYY 267
            |:...|.:|.||..||||.||:.:|:....|:..|     ||||.:| ...|..::..|.||.|:
pombe   192 LLQTEAPLDISDVCGMNLWDIQNEKFDIRLLEEVAGNSKGPDLANKLGTVEINGAKHLGPIGKYF 256

  Fly   268 VKRWNFRPDCMVVASTGSKASELAGL-LVENDFLMLSLDTSDVVVMPLKKAPRLEDGHVMCHPTR 331
            ||::.|.|:|.::..||...:.:..| |.....::|||.||...:|..:......:.|:..||..
pombe   257 VKKYGFSPNCQIIPLTGDNPATILSLPLRPGKDVLLSLGTSTTALMATQNYVCSPEYHMFAHPVT 321

  Fly   332 RDEYMGLLCFQNGGLTRKAICEDV-------AGGSWRHFYEML---DATPSGNNGNVAVHFRDRE 386
            ::.||.:||::||.|.|:.:...:       ...||..|.|.:   :...:|....:.:.:..||
pombe   322 QNHYMVMLCYKNGSLAREQVRNTINEKYNVSDNTSWDRFNESILNPNIKGAGEKKQLGLFYPQRE 386

  Fly   387 IIP-TAKGTLRWDAHISPMSAECIRGLHRFST---------PEIEVRALIEGQIMHHWSIAHEMG 441
            |:| ...||.|:          .|:|...:..         |:.:..|::|.|.:       ::.
pombe   387 ILPAVGPGTWRF----------AIQGTELYQVDKDEESWDYPDEDASAIVESQNL-------DIR 434

  Fly   442 FHHTP-------NTKIIVVGEDSRCQSVLQIVADIFNAPVY--QRTGVEVSLLGCAFRARYA 494
            ...||       ..::.|||..||.::::..::.:....||  :..|.....:|.|.:|.||
pombe   435 MRITPLLTGIPQPDRVYVVGGASRNEAIVFKISQVLGCDVYRLKHGGSNACAVGGAIKAAYA 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3544	NP_001259842.1	FGGY_D-XK_euk	13..493	CDD:212660	156/514 (30%)
CG3544	NP_001259842.1	XylB	15..494	CDD:273550	156/514 (30%)
SPCPJ732.02c	NP_001342982.1	FGGY_D-XK_euk	1..495	CDD:212660	156/514 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	130	1.000	Domainoid score	I1328
eggNOG	1	0.900	-	-		E1_COG1070
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	265	1.000	Inparanoid score	I731
OMA	1	1.010	-	-		QHG56396
OrthoFinder	1	1.000	-	-		FOG0004391
OrthoInspector	1	1.000	-	-		otm47265
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10196
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3110
TreeFam	1	0.960	-	-
	11	10.930