Protein Alignment GABA-B-R3 and olfcu1

DIOPT Version :9

• Sequence 1: NP_001245826.1
• Gene: GABA-B-R3 / 33248
• FlyBaseID: FBgn0031275
• Length: 1305
• Species: Drosophila melanogaster
• Sequence 2: NP_001076368.1
• Gene: olfcu1 / 794431
• ZFINID: ZDB-GENE-050419-175
• Length: 868
• Species: Danio rerio
• Alignment Length: 905
• Identity: 195/905 - (21%)
• Similarity: 324/905 - (35%)
• Gaps: 250/905 - (27%)

  Fly   151 GKIVLLGLFELSTSRGPRPD-GLSEL---------------GAATM--AVEHIN-RKRLLPG--- 193
            |.||:.|||.:. :..|..| ..|:|               ...||  |:|.|| ...||||
Zfish    44 GDIVIGGLFPMH-NIAPETDYNFSDLPHYQDCSRFDFRAFRWVQTMVFAIEEINSNSSLLPGVAL 107

  Fly   194 -------------------YTLELVTNDTQCDPGVGVDRFFHAIYTQPSTRMVMLLGSACSEVTE 239
                               :.|......||.| .||.   .:.:.|.|   :..::|.|.|..|.
Zfish   108 GYRILDSCDHVHTSLRSALFLLNGTFGQTQTD-AVGT---ANCLSTAP---VPAVIGLASSSPTR 165

  Fly   240 SLAKVVPYWNIVQVSFGSTSPALSDRREFPYFYRTVAPDSSHNPARIAFIRKFGWGTVTTFSQNE 304
            ::|:.:..:.|..:|:.:|...|:|::|:|.|.|||..|.......:..:..|||..|.|...::
Zfish   166 AVAQTLGPFGIPLISYFATCTCLTDKKEYPSFLRTVPSDRFQVQGLVQLVSHFGWRWVGTVGTDD 230

  Fly   305 EVHSLAVNNLVTELEAANISCAA---TITFAATDFKEQLLL--LRETDTRIIIGSFSQELAPQIL 364
            :.....:.....:||... ||.|   ||..:.:..:.:.:|  |..:..::||...::....::|
Zfish   231 DYSHYGIQAFTEQLERLG-SCIAFHQTIPKSPSQAQIRSILNSLESSTAQVIIAFATEGELLELL 294

  Fly   365 CEAYRLRMFGADYAWILHESMGAPWWPDQRTACSNHELQLAVENLIVVSTHNSIVGNNVSYS--- 426
            .|..|..:  ....|:..|:     |             :..:.|.:...|..::| .|.:|
Zfish   295 VEVARRNL--TRLQWVASEA-----W-------------VTAKLLTIPELHPVLIG-TVGFSFRG 338

  Fly   427 ----GLNNHMF--NSQLRKQSA--QFHGQDGFGSGYGSRISIAATQSDSRRRRRRGVGGTSGGHL 483
                ||...:|  ....|.:||  ....::.||...|...|     :||      .:...:|...
Zfish   339 TAIPGLAEFLFRVRPSSRPESAFTNMFWEELFGCRLGYEDS-----NDS------VLPLCTGSEN 392

  Fly   484 FPEAISQYAP--------QTYDAVWAIALALRAAEEHWRRNEEQSKLDGFDY---TRSDMA-WEF 536
            ..|..|.|..        ..|.||:|||.||.      :..:..||..|.|:   |.|..: .:.
Zfish   393 LLETESSYTDVSRVRISYNVYKAVYAIAHALH------QLLQCGSKEQGSDHSCNTESKFSPLQL 451

  Fly   537 LQQMGKLHFL--------------------------GVSGPVSFSGPDRVGTTAFY--------- 566
            |:.:.|:||.                          ...|.::|   ..|||   |
Zfish   452 LRYLKKVHFTNQFNEKVYFDTNGEPVPLYDIINWQKNARGTINF---QLVGT---YDGSAPHGQQ 510

  Fly   567 -QIQRGLLE--------PVALYYP--------AT---------DALD------------FRCPRC 593
             :|:.||:.        ||:|..|        ||         |.|.            ..|.:|
Zfish   511 LKIEEGLIRWTGGQTKVPVSLCSPPCPPGTRQATRPGQPVCCFDCLPCAEGEISNISGATECLKC 575

  Fly   594 RPVKWHSGQVPIAKRVFKLRVATIAP----LAFYTI-----ATLSSVGIALAIAFLAFNLHFRKL 649
            ....|.:          |.||:.:|.    |:::.:     .:||..|:|:|...:.....||..
Zfish   576 PEYYWPN----------KERVSCVAGIEEFLSYHDVMGIILISLSLFGVAVATVVMVIFFIFRST 630

  Fly   650 KAIKLSSPKLSNITAVGCIFVY-ATVILLGLDHSTLPSAEDSFATVCTARVYLLSAGFSLAFGSM 713
            ..:|.::.::|.:..:.....: .:::.:|     .||     ...|.||.......|.|....:
Zfish   631 PIVKANNSEMSFLLLLSLKLCFLCSLVFVG-----RPS-----PLTCRARQAAFGISFVLCISCI 685

  Fly   714 FAKTYRVHRIFTRT--GSVFKDKMLQDIQLILLVGGLLLVDALLVTLWVVTDPMERHLHNLTLEI 776
            ..||..|...|..|  ||: ..|:....|..:.:........:|...|:...|...:.:.
Zfish   686 LVKTIVVLLAFRSTVPGSI-SLKVFGPPQQRVFIFCCTTGQVILCACWLALAPPYPYKNT----- 744

  Fly   777 SATDRSVVYQPQVEVCRSQHTQTWLSVLYAYKGLLLVVGVYMAWETRHVKIP-ALNDSQYIGVSV 840
            |..|..::.:     |:......:..|| .|.|||..:...:|:..|  |:| ..|:::.|   .
Zfish   745 SYQDGRIILE-----CKDILPLGFYLVL-GYIGLLSCMCFVLAFLGR--KLPDTFNEAKLI---T 798

  Fly   841 YSVVITSAI---VVVLANLISERVTLAFITITALILTSTTATLCLLFIPKLHDIWARNDI 897
            :|::|..|:   .:...|....:.|:| :.|.| ||.||...|..:||||.:.|..|.|:
Zfish   799 FSMLIFCAVWISFIPAYNSSPGKYTVA-VEIFA-ILASTFGLLFSIFIPKCYVILLRPDL 856

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GABA-B-R3	NP_001245826.1	PBP1_GABAb_receptor	157..590	CDD:107361	120/574 (21%)
		ANF_receptor	174..568	CDD:279440	103/497 (21%)
		7tm_3	633..889	CDD:278433	58/262 (22%)
olfcu1	NP_001076368.1	Periplasmic_Binding_Protein_Type_1	41..520	CDD:299141	115/528 (22%)
		ANF_receptor	83..486	CDD:279440	96/448 (21%)
		NCD3G	529..580	CDD:284890	9/50 (18%)
		7tm_3	614..849	CDD:278433	58/263 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910