Protein Alignment GABA-B-R3 and LOC793043

DIOPT Version :9

• Sequence 1: NP_001245826.1
• Gene: GABA-B-R3 / 33248
• FlyBaseID: FBgn0031275
• Length: 1305
• Species: Drosophila melanogaster
• Sequence 2: XP_001332717.1
• Gene: LOC793043 / 793043
• -ID: -
• Length: 852
• Species: Danio rerio
• Alignment Length: 880
• Identity: 182/880 - (20%)
• Similarity: 298/880 - (33%)
• Gaps: 215/880 - (24%)

  Fly   151 GKIVLLGLF---------ELSTSRGPRPDGLSELG--------AATMAVEHINR-KRLLPGYTLE 197
            |.|::.|:|         :|:.|..|.|.....|.        :...|||.||. ..|:||.:|.
Zfish    40 GDIIIGGVFSFHSSWEIRQLTYSVTPPPLKCISLNYRDFQYVQSMLFAVEEINNSSTLIPGVSLG 104

  Fly   198 LVTNDTQCDPGVGVDRFFHAIYTQ--------PSTRMV---MLLGSACSEVTESLAKVVPYWNIV 251
            ....|| |.......|...|:...        |.|:..   .:||...|....::||.:..:|:.
Zfish   105 YRIYDT-CGSMAMAVRVTMALANAHENTTSDGPCTKQAYVQTILGDTTSSACMAMAKTIGPFNLP 168

  Fly   252 QVSFGSTSPALSDRREFPYFYRTVAPDSSHNPARIAFIRKFGWGTVTTFSQNEEVHSLAVNNLVT 316
            .:|..:|...|||:.::|.|.||:..|...:.|....:|.|||..|.....:::..:..:.....
Zfish   169 MISHYATCECLSDKVKYPSFLRTITSDYYQSRALAELVRHFGWTWVGAIRTDDDYGNNGMATFTK 233

  Fly   317 ELEAANISCAATITFAATDFKEQLLLLRE---TDTRIIIGSFSQELAPQILCEAY-RLRMFGADY 377
            ..|...|....::.|..|..:::::.:.|   :.|..:|.:|......::|...: ...:.|  |
Zfish   234 VAEQMGICLEYSVPFFRTYAEDKVIRIIEQIKSSTSRVIVAFLVHWDLEVLLHKFVEYNITG--Y 296

  Fly   378 AWILHESMGAPWWPDQ--RTACSNHELQLAVENLIVVSTHNSIVGNNVSYSGLNNHMFNSQLRKQ 440
            .|:..|.    |..|.  .|..::|.||.|| .|.:..|         ..:||..::.|.:..|.
Zfish   297 QWVGTEG----WISDSVIATMDTHHILQGAV-GLAIPKT---------EVTGLKEYILNIKQLKS 347

  Fly   441 SAQFHGQDGFGSGYGSRISIAATQSDSRRRRRRGVGGTSGGHLFPEAISQYA------------P 493
            |    |...|...:.|.........|.........|.        |.:||..            .
Zfish   348 S----GSTIFSELWESLYQCKYPNKDDSVSMNACTGN--------EELSQMQNSFTDMSLMPIFS 400

  Fly   494 QTYDAVWAIALALRAAEEHWRRNEEQSKLDGFDYTRSDMAWEFLQQMGKLHFLGVSG-PVSFSGP 557
            ..|..|:|:|..|........:...:.:||..         .||:.:.|:.|....| .|.|
Zfish   401 NVYKGVYAVAHTLHELLGCKEKCASKKQLDPI---------TFLKHLRKVRFKTKDGEDVYF--- 453

  Fly   558 DRVG-TTAFYQI--------QRGLLEPVALY---YPATDAL------------------------ 586
            |..| ..|.|::        :......|.||   .|..|.|
Zfish   454 DENGEAVARYEVINWHPSNGKHDQFVTVGLYDASLPVKDRLAVNVASIVWSNNATKVPVSVCSES 518

  Fly   587 ---------------------------------DFRCPRCRPVKWHSGQ--VPIAKRVFKLRVAT 616
                                             ...|.||....|.:.|  |.:.|....|....
Zfish   519 CSPGTRKAVKKGKFICCYDCISCADGEISNTTDSVTCLRCHQELWSNLQKDVCVEKETEFLSFEE 583

  Fly   617 IAPLAFYTIATLSSVG--IALAIAFLAFNLHFRKLKAIKLSSPKLSNIT--AVGCIFVYATVILL 677
            |..:   .:.|:|.||  :.:.||.:.|  .::....:|.::.:||.:.  ::.|.|: .::..:
Zfish   584 IMGI---LLTTISIVGAFVTMIIAVIFF--RYKNTPIVKANNSELSFLLLFSLMCCFL-CSLTFI 642

  Fly   678 GLDHSTLPSAEDSFATVCTARVYLLSAGFSLAFGSMFAKTYRVHRIFTRT--GSVFKDKMLQDIQ 740
            |      ...|.|    |..|.......|.|....:..||..|...|..|  ||... |.....|
Zfish   643 G------QPTEWS----CMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSNVM-KWFGPPQ 696

  Fly   741 LILLVGGLLLVDALLVTLWVVTDP------MERHLHNLTLEISATDRSVVYQPQVEVCRSQHTQT 799
            ..|.|.|..|:..|:..||:...|      .......:.||                |....:..
Zfish   697 QRLSVLGFTLIQVLICVLWLTISPPFPFKNFNYFKEKIILE----------------CHVGSSIG 745

  Fly   800 WLSVLYAYKGLLLVVGVYMAWETRHVKIP-ALNDSQYIGVSVYSVVITSAIVV--VLANLISERV 861
            :.:|| .|.|.|.::...:|:..|  |:| ..|::::|   .:|::|..|:.:  :.|.:.|...
Zfish   746 FWAVL-GYIGCLALLCFILAFLAR--KLPDKFNEAKFI---TFSMLIFCAVWIGFIPAYVSSPGK 804

  Fly   862 TLAFITITALILTSTTATLCLLFIPKLHDIWARND 896
            ....:.|.| ||.|:...|..:|:||.:.|..:.|
Zfish   805 FTVAVEIFA-ILASSFGLLFCIFLPKCYVILFKPD 838

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GABA-B-R3	NP_001245826.1	PBP1_GABAb_receptor	157..590	CDD:107361	105/549 (19%)
		ANF_receptor	174..568	CDD:279440	93/433 (21%)
		7tm_3	633..889	CDD:278433	60/268 (22%)
LOC793043	XP_001332717.1	PBP1_GPCR_family_C_like	43..487	CDD:153138	102/484 (21%)
		ANF_receptor	82..469	CDD:279440	92/427 (22%)
		NCD3G	512..563	CDD:284890	3/50 (6%)
		7tm_3	597..832	CDD:278433	60/271 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910