Protein Alignment GABA-B-R3 and Vmn2r87

DIOPT Version :9

• Sequence 1: NP_001245826.1
• Gene: GABA-B-R3 / 33248
• FlyBaseID: FBgn0031275
• Length: 1305
• Species: Drosophila melanogaster
• Sequence 2: NP_001096836.1
• Gene: Vmn2r87 / 625131
• MGIID: 3645796
• Length: 848
• Species: Mus musculus
• Alignment Length: 875
• Identity: 162/875 - (18%)
• Similarity: 278/875 - (31%)
• Gaps: 282/875 - (32%)

  Fly   181 AVEHINRK-RLLPGYTLELVTNDTQCDPGVGV---------DRFFHAIYT--QPSTRMVMLLGSA 233
            |.:.||:. .|||..:|.......:|...:|:         |...:..|.  ...|.::.|.|.:
Mouse    84 ATDEINKNPDLLPNTSLVFSVIGGKCQDSLGLLGEEYILINDSLNYVNYVCKADDTCVIDLTGPS 148

  Fly   234 CSEVTESLAKVVPYWNIVQVSFGSTSPALSDRREFPYFYRTVAPDSSHNPARIAFIRKFGWG--- 295
            ..   .||...:..|. .:|.||..:|.|||...|||.::....|:..:...::.:..|.|.
Mouse   149 WK---TSLKLAIDSWT-PKVFFGPFNPNLSDHDRFPYVHQVATKDTHLSHGMVSLMLHFRWTWIG 209

  Fly   296 -TVTTFSQNEEVHS------------LAVNNLVTELEAANISCAATITFAATDFKEQLLLLRETD 347
             .::...|..::||            ||..|::.|        ...|.....:..::.::.....
Mouse   210 LVISDDDQGIQLHSDLREESQRHGICLAFVNVIPE--------TMKIYMTRGNMYDKQIMTSSAK 266

  Fly   348 TRIIIGSFSQELAPQILCEAYRLRMFGADYAWILHESMGAPWWPDQRTACSNHELQLAVENLIVV 412
            ..||.|..:..|........|    .||...||....     | |..|...:..|.| ....:..
Mouse   267 VVIIYGEMNSTLEISFRRWVY----LGARRIWITTSQ-----W-DVITNKKDFSLDL-FHGTVTF 320

  Fly   413 STHNSIVGN---------------NVSYSGLNNHMFNSQLRKQSAQFHGQDGFGSGYGSRISIAA 462
            :.|...:..               |:|.|.|..:.||..:.|.|.:   .|.|..
Mouse   321 AHHKGWIAKFKNFMQTMNTSKYPINISQSVLRWNYFNCSVSKNSIK---MDHFTC---------- 372

  Fly   463 TQSDSRRRRRRGVGGTSGGHLFPEAISQYAPQTYDAVWAIALALRAAEEHWRRNEEQSKL--DGF 525
                     :..:..|: .|.:..|:|......|:||:|:|   .|..||.....|..|:  |..
Mouse   373 ---------KNPLEWTA-LHNYDMALSDEGYNLYNAVYAVA---HAYHEHILHQVESQKMAEDKG 424

  Fly   526 DYTRSDMAWEFLQQMGKLHFLGVSGPVSFSGP--------DRVGTTAFYQI--------QRGLLE 574
            .||.       .||:..|....|     |:.|        .|....|.|.|        ..||..
Mouse   425 KYTE-------CQQLAPLLKTRV-----FTNPVGELVNMNQREYQCAEYDIFIIWNFPQGLGLKV 477

  Fly   575 PVALYYPATDALDFRC-PRCR------PVKWHSGQ------------VPIAKRVFKLRVA----- 615
            .:..|:|        | ||.:      .::|.:|.            .|..:::.:...|
Mouse   478 KIGNYFP--------CFPRSQQLHISEDLEWVTGGTLVPSSMCSVTCTPGFRKIHQKETADCCFD 534

  Fly   616 --------------------------------------TIAPLAF-----YTIATLSSVGIALAI 637
                                                  |::.||:     ..:.:::....|:.|
Mouse   535 CVQCPENEVSNETADMEQCVRCPDDKYANLEQSHCLQRTVSFLAYEDPLGMVLGSMALSSSAITI 599

  Fly   638 AFLAFNLHFRKLKAIKLSSPKLSNITAVGCIFVYATVILLGLDHSTLPSAEDSFATVCTARVYLL 702
            ..|...:.::....:|.::..||.|..:..:|.:...:|. ::|..        ...|..:....
Mouse   600 LVLVTFMKYKDTPIVKANNCILSYILLISLVFCFLCSLLF-IEHPN--------QVTCILQQTTF 655

  Fly   703 SAGFSLAFGSMFAKTYRVHRIF--TRTGSVFKDKMLQDIQLILLVGGLLLVDALLVTLWVVTDPM 765
            ...|::|..::.|||..|...|  |..|...:..|....:|::.:  ..|:..:|..:|::|.|
Mouse   656 GLFFTVAVSTVLAKTITVVMAFKLTTPGKRMRGMMTGAPKLVIPI--CTLIQLVLCGIWLLTSP- 717

  Fly   766 ERHLHNLTLEISATDRSVVYQPQVEVCRSQHTQTWLSVLYAYKGLLLVVGVYMAWETRHVKIPAL 830
                       ...||.:         :|:|.:|   |::..||.::...|.:.
Mouse   718 -----------PFIDRDI---------QSEHGKT---VIFCNKGSVIAFHVVLG----------- 748

  Fly   831 NDSQYIGVSVYSVVITSAIVVVLANLISERVTLA-FITITAL----------------------- 871
                |:|    |:.:.|..|..||..:.:|...| |:|.:.|
Mouse   749 ----YLG----SLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGKIMVV 805

  Fly   872 -----ILTSTTATLCLLFIPKLHDIWARND 896
                 ||.|:...|..:|:||.:.|..|.|
Mouse   806 VEVFSILASSAGLLGCIFVPKCYVILVRPD 835

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GABA-B-R3	NP_001245826.1	PBP1_GABAb_receptor	157..590	CDD:107361	94/469 (20%)
		ANF_receptor	174..568	CDD:279440	89/439 (20%)
		7tm_3	633..889	CDD:278433	55/286 (19%)
Vmn2r87	NP_001096836.1	PBP1_Pheromone_receptor	40..500	CDD:107360	97/484 (20%)
		NCD3G	509..561	CDD:284890	2/51 (4%)
		7tm_3	596..829	CDD:278433	55/286 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910