Protein Alignment GABA-B-R3 and npr3

DIOPT Version :9

• Sequence 1: NP_001245826.1
• Gene: GABA-B-R3 / 33248
• FlyBaseID: FBgn0031275
• Length: 1305
• Species: Drosophila melanogaster
• Sequence 2: XP_005165413.1
• Gene: npr3 / 569395
• ZFINID: ZDB-GENE-060531-91
• Length: 503
• Species: Danio rerio
• Alignment Length: 506
• Identity: 97/506 - (19%)
• Similarity: 163/506 - (32%)
• Gaps: 181/506 - (35%)

  Fly   210 GVDRFFHAIYTQPSTRMVMLLGSACSEVTESLAKVVPYWNIVQVSFGSTSPALSDRREFPYFYRT 274
            |:|..:..:..|...|..::||..|.....|:.:|..:|||..:|.|:.:...:.:
Zfish    79 GMDALYALVDRQKDERPDLVLGPVCEYAASSVTRVASHWNIPVISAGALATGFNSK--------- 134

  Fly   275 VAPDSSH----NPARI-------AFIRKFGWGT---VTTFSQNEEVHSLAVNNLVTELEAANISC 325
             .|:.||    .|..:       |....|||.|   :....::|......:..:.|.|...:||
Zfish   135 -TPEYSHLTRIAPTYLKMAETFQAIFGHFGWRTAYLIYDDDKDERNCYFTMEGVFTVLSEYHIS- 197

  Fly   326 AATITFAATDFKEQLLLLRETDTRIIIGSFSQELAPQ-ILCEAYRLRMFGADYAWILHESMGAPW 389
                    |||             .::.|..:.:.|. |:...|     |::..
Zfish   198 --------TDF-------------AVLNSNEERVDPDGIITSVY-----GSEVV----------- 225

  Fly   390 WPDQRTACSNHELQLAVENLIVVSTHNSIVGNNVSYSGLNNHMFNSQLRKQSAQFHGQDGFGSGY 454
                 ..||..::   |.:|::.:....:..:  |:...|..:|||                |.|
Zfish   226 -----IMCSKADI---VRDLMLAAHRRKLTSD--SHIFFNIELFNS----------------SSY 264

  Fly   455 GSRISIAATQSDSRRRRRRGVGGTSGGHLF-----------PE---------------------- 486
            |         ..|.|||.:........:.|           ||
Zfish   265 G---------DGSWRRRDKYDDEARAAYSFLNTVTLLRSTKPEFEDFSIEMKKSLQQSNIPICED 320

  Fly   487 --AISQYAPQTYDAVWAIALALRAAEEHWRRNEEQSKLDGFDYTRSDMAWEFLQQMGKLHFLGVS 549
              |::.:....:||:...|:|||..     :::..:|.:|.:.|.|         |....|.|::
Zfish   321 CSAVNMFMEGFHDALLLYAIALREV-----KSKGLTKKNGLEITHS---------MWNRTFEGIA 371

  Fly   550 GPVSF-SGPDRVGTTAFYQI---QRGLLEPVALYYPATDALDFRCPRCRPVKWHSGQVPIAKRV- 609
            |.||. :..||.|..:..::   :.|..|.|..|:....:...              :|..||.
Zfish   372 GQVSLDANGDRNGDFSVVRMTDPESGKHETVMNYFGTNGSFQI--------------LPGFKREW 422

  Fly   610 FKLRVATIAP-------------LAFYTIATLSSVGIALAIAFLAFNLHFR 647
            |.||  ||.|             .|...|.....:|.||.:||..|..::|
Zfish   423 FSLR--TIPPPKPLDPSSGGLGVSAVTGIIVGGILGTALLLAFYFFRKNYR 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GABA-B-R3	NP_001245826.1	PBP1_GABAb_receptor	157..590	CDD:107361	79/433 (18%)
		ANF_receptor	174..568	CDD:279440	75/408 (18%)
		7tm_3	633..889	CDD:278433	6/15 (40%)
npr3	XP_005165413.1	Periplasmic_Binding_Protein_Type_1	29..416	CDD:299141	79/447 (18%)
		ANF_receptor	46..389	CDD:279440	75/406 (18%)
		TM_EphA1	436..468	CDD:214014	8/31 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910