Protein Alignment GABA-B-R3 and C30A5.10

DIOPT Version :9

• Sequence 1: NP_001245826.1
• Gene: GABA-B-R3 / 33248
• FlyBaseID: FBgn0031275
• Length: 1305
• Species: Drosophila melanogaster
• Sequence 2: NP_498793.3
• Gene: C30A5.10 / 3565865
• WormBaseID: WBGene00016242
• Length: 988
• Species: Caenorhabditis elegans
• Alignment Length: 1054
• Identity: 202/1054 - (19%)
• Similarity: 339/1054 - (32%)
• Gaps: 373/1054 - (35%)

  Fly    23 VLALAWATSAAAAMESSAELQALGYEAIRPGAASISTSS---PSSSPPGESASTVTAGGTPIPP- 83
            |..:||....:....||            |.|::||..|   ||:.|...:|||.|: .|.:||
 Worm    84 VSQVAWNPPVSTNPSSS------------PAASTISFQSYQNPSTFPSTTTASTTTS-TTTMPPT 135

  Fly    84 ------------RSDWKYKRTKVK----RRQQRLNSHSNLPGSTNASHA------HHLLN----L 122
                        .:.|...::.:|    .:..:||..|:...:|:...|      |.|||    :
 Worm   136 YQTTTKSVKKNTETLWTTSKSPMKLSKNPKPSKLNQKSSKSSATSFDSAQLSVLSHRLLNDVLII 200

  Fly   123 PPRQRYLKVNQVFESERRMSPAEMQRNHGKIVLLGLFELSTSRGPR--------PDGLSELGAAT 179
            |             |.||            :.:|.:..:..|.|.:        .:.:..:.|..
 Worm   201 P-------------SSRR------------LYILAIIPIHQSSGQQNFECGEIDVNAIVRMAAFL 240

  Fly   180 MAVEHINRKRLLPGYTLELVTNDTQCDPGVGVDRFFHAIYTQPSTRMVMLLGSACSEVTESLAKV 244
            .|.:.||...||               ..:|||             :..::..:||....|:|
 Worm   241 EAQKTINESNLL---------------KEIGVD-------------IGAIIVDSCSTDLRSVA-- 275

  Fly   245 VPYWNIVQVSFGSTSPALSDRREFPYFYRTVAPDSSHNPARIAFIRKFGWGTVTTF--------- 300
                ::.::..| |:...||      ....:..||:..|.....||:.....|.||
 Worm   276 ----DLYELLSG-TNIQKSD------LIAIIRDDSTFMPNTEQIIRQLNLPVVNTFFTTRSAVQT 329

  Fly   301 ---------------SQNEEVHSLAVNNLVTELEAANIS-----------C---AATITFAATDF 336
                           |......|..||.:..|..:.::|           |   |..:..|::..
 Worm   330 SGTLPSMFLPIQSIISALRHYQSTCVNIIFDEKYSESVSEFQQVALTEGICVEVAIHVKNASSTV 394

  Fly   337 KEQL---LLLRETDTRIIIGSFSQELAPQILCEAYRLRMFGA---------DYAWILHESMGAPW 389
            .|.:   |||.|  .||::...|::...| :.:|.|..|..|         |..|.........|
 Worm   395 SEMVVRRLLLSE--ARIVVALLSEDTWIQ-MTKALRSEMVIAGRFVFISMQDQRWTTSRKFIESW 456

  Fly   390 WPDQRTACS-------NH--ELQLAVENLIVVSTHNSIVGNNVSYSGLNNHMFNSQLRKQSAQFH 445
            ...::...|       ||  |::...||:..:|..|               ::..|....:.:.|
 Worm   457 PTFEQHLISITPKTPINHEEEIKKLTENIPKLSLPN---------------LWLKQFWSSAFKCH 506

  Fly   446 --GQDGFGSGYGSRISIAATQSDSRRRRRRGVGGTSGGHLFPEAISQYAPQTYDAVWAIALALRA 508
              .:|..||...|| ..|.|||.:                    |||.||..  .|.:|:||..|
 Worm   507 VDNEDMGGSNSFSR-ECATTQSLN--------------------ISQVAPDV--DVASISLATHA 548

  Fly   509 AEEHWRR------------------NE-----EQSKLDG-FDYTRSDMAWEFLQQMG-------- 541
            ....:|.                  |:     .||.||. |.:..||:...|....|
 Worm   549 IGIAFRSFVDRVCPGALVISLSDCVNDPFVGFHQSILDSDFVHHLSDIPVSFNYSTGFRDISLRI 613

  Fly   542 --------KLHF--LGVSGPVSFSGPDRVGTTAFYQIQRGLLEPVA----LYYPATDALDFRCPR 592
                    :|.|  ||:..|:.|:          ||.......|.|    |...:|      ||:
 Worm   614 NRVQFVEDRLQFSELGIVDPIQFT----------YQDSSDTATPSARGSYLLMSST------CPK 662

  Fly   593 CRPVKWHSGQVPIAKRVFKLRVATIA------PLAFYTIATLSSVGIALAIAFLAFNLHFRKLKA 651
            ....|      .:||...|.::.:|.      .:..:||.::.|....|...:         ||.
 Worm   663 STCAK------ELAKSTIKQQLPSIVKALTDLEIMIFTIFSVLSALTCLMCMY---------LKV 712

  Fly   652 IKLSSPKLSNITAVGCIFVYATVILLGLDHSTLPSAEDSFATVCTARVYLLSAGFSLAFGSMFAK 716
            |.:|  :..|:|||  .|:....:.:......:|....|    |:.|..|.....|:....:|.|
 Worm   713 ISVS--EYRNLTAV--TFLGLAFLSISAPAFIIPPNSIS----CSLRKLLFPIAISITIAPVFVK 769

  Fly   717 TYRVHRIFTRTGSVFKDKMLQDIQLILLVGGLLLVDALLVTLWVVTDPMERHLHNLTLEISATDR 781
            |..:.:....:.|           .:|:...::|:..::.|.|:           |....|||
 Worm   770 TVLIWKSIGSSSS-----------SVLIAFCIVLIQTVISTEWL-----------LLASDSAT-- 810

  Fly   782 SVVYQPQVEVCRSQHTQTW-----------LSVLYAYKGLLLVVGVYMAWET-RHVKIPALNDSQ 834
                    |...:.|...|           :.:..:...||.::....|..| :|.:     ..|
 Worm   811 --------EFVSTLHGTMWRCSPGDSSEEMILLSCSLIALLSLLSFIFALATLKHSQ-----SLQ 862

  Fly   835 YIGVSVYSVVITSAIVVVLANLISER-------VTLAFITITALILTST------TATLCLLFIP 886
            ::.:|:.:::..:|:.|.|. ||..:       .|:......||:|:.|      ..:.|...:.
 Worm   863 HLMISILAILFETALYVSLP-LIPYKTRDTVMATTILIFAFVALLLSHTGKSSAKKESECGGTLQ 926

  Fly   887 KLHDIWARNDIIDP 900
            |.::.|.::.:..|
 Worm   927 KTNENWLQHVVQSP 940

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GABA-B-R3	NP_001245826.1	PBP1_GABAb_receptor	157..590	CDD:107361	104/547 (19%)
		ANF_receptor	174..568	CDD:279440	97/496 (20%)
		7tm_3	633..889	CDD:278433	50/280 (18%)
C30A5.10	NP_498793.3	Periplasmic_Binding_Protein_Type_1	213..>528	CDD:299141	70/374 (19%)
		7tm_3	719..>792	CDD:278433	16/89 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910